Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2931508..2932166 Replicon chromosome
Accession NZ_CP042331
Organism Bosea sp. F3-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FQV39_RS13500 Protein ID WP_149130760.1
Coordinates 2931508..2931930 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FQV39_RS13505 Protein ID WP_149130761.1
Coordinates 2931927..2932166 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQV39_RS13475 2926585..2927442 + 858 WP_149130755.1 3-keto-5-aminohexanoate cleavage protein -
FQV39_RS13480 2927433..2928641 + 1209 WP_149130756.1 3-oxoadipate enol-lactonase -
FQV39_RS13485 2928638..2929348 + 711 WP_149130757.1 CoA transferase subunit A -
FQV39_RS13490 2929363..2930019 + 657 WP_149130758.1 CoA transferase subunit B -
FQV39_RS13495 2930122..2931399 + 1278 WP_149130759.1 polyhydroxyalkanoate depolymerase -
FQV39_RS13500 2931508..2931930 - 423 WP_149130760.1 type II toxin-antitoxin system VapC family toxin Toxin
FQV39_RS13505 2931927..2932166 - 240 WP_149130761.1 plasmid stability protein Antitoxin
FQV39_RS13510 2932305..2933234 - 930 WP_149130762.1 LysR family transcriptional regulator -
FQV39_RS13515 2933340..2934113 + 774 WP_149130763.1 protocatechuate 3,4-dioxygenase subunit beta -
FQV39_RS13520 2934117..2934743 + 627 WP_149130764.1 protocatechuate 3,4-dioxygenase subunit alpha -
FQV39_RS13525 2934749..2934964 + 216 Protein_2687 transposase -
FQV39_RS13530 2935140..2936549 - 1410 WP_149130765.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14766.98 Da        Isoelectric Point: 5.1409

>T135402 WP_149130760.1 NZ_CP042331:c2931930-2931508 [Bosea sp. F3-2]
MIVLDTNVISEPLRPAGEPAVLAWLDQQNIETLFLTTISLAELRYGVAALPDGRRKEGLGAALERRIIVLFGPRILPFDS
DAADAYALIRTRAKAAGRAIGAADGYIAATAAAHGFTVATRDTGPFEAAGLPVINPWATV

Download         Length: 423 bp

>T135402 NZ_CP042331:c2931930-2931508 [Bosea sp. F3-2]
ATGATCGTCCTGGATACAAATGTCATCTCCGAGCCGCTGAGGCCGGCCGGTGAACCGGCCGTGCTCGCTTGGCTCGATCA
ACAGAATATCGAGACGCTTTTCCTGACCACGATCAGCTTGGCCGAGCTTCGCTATGGCGTTGCGGCTTTGCCCGATGGTC
GACGTAAAGAAGGCCTGGGCGCGGCCTTGGAGAGGCGCATCATCGTCCTGTTTGGGCCGCGAATACTTCCCTTCGATTCC
GACGCTGCCGACGCCTATGCCCTGATCCGTACCCGCGCCAAAGCTGCAGGCAGGGCGATTGGTGCGGCAGACGGCTATAT
TGCCGCGACGGCCGCAGCACATGGCTTCACCGTGGCAACGCGCGACACCGGACCTTTTGAAGCCGCCGGGCTGCCCGTCA
TCAATCCGTGGGCGACGGTCTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8700.88 Da        Isoelectric Point: 6.7274

>AT135402 WP_149130761.1 NZ_CP042331:c2932166-2931927 [Bosea sp. F3-2]
MPAVTIRNLPEATHRALKLRAAQHGRSTEAEIRDIIESAVRPHDRIKLGTELAAIGREFGGVELEIERDKTPAGTVSFE

Download         Length: 240 bp

>AT135402 NZ_CP042331:c2932166-2931927 [Bosea sp. F3-2]
ATGCCTGCCGTCACAATCAGAAACTTGCCCGAAGCGACACATAGAGCGCTCAAGCTGCGGGCCGCCCAACATGGTCGGAG
CACTGAGGCGGAAATCCGCGACATCATCGAAAGCGCCGTTCGGCCACATGATCGGATCAAGCTCGGCACCGAGCTGGCCG
CGATCGGGCGGGAGTTTGGCGGCGTGGAACTCGAAATCGAGCGCGACAAGACGCCGGCCGGTACGGTGAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References