Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 234807..235225 Replicon chromosome
Accession NZ_CP042331
Organism Bosea sp. F3-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FQV39_RS33470 Protein ID WP_210251155.1
Coordinates 234807..234941 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FQV39_RS01130 Protein ID WP_149128634.1
Coordinates 234944..235225 (+) Length 94 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQV39_RS01115 231441..232649 + 1209 WP_149133591.1 MFS transporter -
FQV39_RS01120 232646..233374 + 729 WP_149128632.1 siderophore-iron reductase FhuF -
FQV39_RS01125 233484..234674 + 1191 WP_149128633.1 elongation factor Tu -
FQV39_RS33470 234807..234941 + 135 WP_210251155.1 addiction module killer protein Toxin
FQV39_RS01130 234944..235225 + 282 WP_149128634.1 putative addiction module antidote protein Antitoxin
FQV39_RS01135 235380..235664 + 285 WP_149128635.1 putative addiction module antidote protein -
FQV39_RS01140 235770..236669 + 900 WP_149128636.1 dihydrodipicolinate synthase family protein -
FQV39_RS01150 236859..237590 + 732 WP_149128637.1 methyltransferase domain-containing protein -
FQV39_RS01155 237754..237948 + 195 WP_149128638.1 preprotein translocase subunit SecE -
FQV39_RS01160 237963..238496 + 534 WP_149128639.1 transcription termination/antitermination protein NusG -
FQV39_RS01165 238601..240214 + 1614 WP_149128640.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(4-92)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4989.83 Da        Isoelectric Point: 10.3516

>T135399 WP_210251155.1 NZ_CP042331:234807-234941 [Bosea sp. F3-2]
MRIDYGYRLYFVQQGKTLVILLGGGDKRTQSADIAKARQMAKDL

Download         Length: 135 bp

>T135399 NZ_CP042331:234807-234941 [Bosea sp. F3-2]
ATGCGGATCGACTACGGCTATCGGCTGTACTTCGTGCAGCAGGGCAAGACATTGGTGATCCTGCTGGGCGGCGGAGACAA
GCGGACGCAATCGGCGGATATCGCCAAAGCCAGGCAGATGGCGAAGGACCTGTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10100.64 Da        Isoelectric Point: 6.3201

>AT135399 WP_149128634.1 NZ_CP042331:234944-235225 [Bosea sp. F3-2]
MPLETTKFDIQTYLKTPEQQAAYIEAALEENDPAFLAKALGDVARARGMTQVAKDAGVTREALYRALSEKGDPRLSTFMG
VLNSLGLKLKIAA

Download         Length: 282 bp

>AT135399 NZ_CP042331:234944-235225 [Bosea sp. F3-2]
ATGCCCCTCGAAACCACCAAGTTCGACATCCAGACCTATCTCAAGACGCCTGAGCAGCAGGCCGCCTATATCGAAGCGGC
GCTCGAGGAAAACGACCCGGCTTTCCTTGCGAAGGCGCTCGGGGATGTTGCGCGCGCGCGCGGCATGACGCAGGTCGCCA
AGGATGCAGGCGTGACCCGCGAAGCACTTTACCGCGCCCTCAGCGAGAAGGGCGATCCGCGCCTATCCACCTTCATGGGC
GTGCTCAACTCCCTCGGGCTGAAACTGAAGATCGCGGCCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References