Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 3164450..3164921 Replicon chromosome
Accession NZ_CP042326
Organism Euhalothece natronophila Z-M001

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FRE64_RS15585 Protein ID WP_146297072.1
Coordinates 3164450..3164710 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FRE64_RS15590 Protein ID WP_146297073.1
Coordinates 3164700..3164921 (+) Length 74 a.a.

Genomic Context

FRE64_RS15555FRE64_RS15560FRE64_RS15575FRE64_RS15580FRE64_RS15585FRE64_RS15590FRE64_RS15595FRE64_RS15545FRE64_RS15550FRE64_RS15565FRE64_RS15570FRE64_RS15600FRE64_RS15605FRE64_RS15610FRE64_RS15615FRE64_RS15620FRE64_RS15625FRE64_RS15630
Location: 3160589..3161218 (630 bp)
Type: Others
Protein ID: WP_146297066.1
Location: 3161255..3161719 (465 bp)
Type: Others
Protein ID: WP_146297067.1
Location: 3162771..3163862 (1092 bp)
Type: Others
Protein ID: WP_146297070.1
Location: 3164182..3164394 (213 bp)
Type: Others
Protein ID: WP_146297071.1
Location: 3164450..3164710 (261 bp)
Type: Toxin
Protein ID: WP_146297072.1
Location: 3164700..3164921 (222 bp)
Type: Antitoxin
Protein ID: WP_146297073.1
Location: 3165086..3166177 (1092 bp)
Type: Others
Protein ID: WP_146297074.1
Location: 3159631..3160098 (468 bp)
Type: Others
Protein ID: WP_146297064.1
Location: 3160195..3160446 (252 bp)
Type: Others
Protein ID: WP_146297065.1
Location: 3161870..3162490 (621 bp)
Type: Others
Protein ID: WP_146297068.1
Location: 3162515..3162751 (237 bp)
Type: Others
Protein ID: WP_146297069.1
Location: 3166258..3166704 (447 bp)
Type: Others
Protein ID: WP_146297395.1
Location: 3166707..3166943 (237 bp)
Type: Others
Protein ID: WP_146297075.1
Location: 3167704..3168057 (354 bp)
Type: Others
Protein ID: WP_186708878.1
Location: 3168143..3168515 (373 bp)
Type: Others
Protein ID: Protein_3081
Location: 3168512..3168751 (240 bp)
Type: Others
Protein ID: WP_146297077.1
Location: 3168846..3169181 (336 bp)
Type: Others
Protein ID: WP_146297078.1
Location: 3169178..3169480 (303 bp)
Type: Others
Protein ID: WP_146297397.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FRE64_RS155453159631..3160098-468WP_146297064.1Hsp20/alpha crystallin family protein-
FRE64_RS155503160195..3160446-252WP_146297065.1hypothetical protein-
FRE64_RS155553160589..3161218+630WP_146297066.1phosphoribosylglycinamide formyltransferase-
FRE64_RS155603161255..3161719+465WP_146297067.1NADAR family protein-
FRE64_RS155653161870..3162490-621WP_146297068.1cyanoexosortase A system-associated protein-
FRE64_RS155703162515..3162751-237WP_146297069.1hypothetical protein-
FRE64_RS155753162771..3163862+1092WP_146297070.1ISAs1 family transposase-
FRE64_RS155803164182..3164394+213WP_146297071.1hypothetical protein-
FRE64_RS155853164450..3164710+261WP_146297072.1BrnT family toxinToxin
FRE64_RS155903164700..3164921+222WP_146297073.1CopG family transcriptional regulatorAntitoxin
FRE64_RS155953165086..3166177+1092WP_146297074.1ISAs1 family transposase-
FRE64_RS156003166258..3166704-447WP_146297395.1hypothetical protein-
FRE64_RS156053166707..3166943-237WP_146297075.1hypothetical protein-
FRE64_RS156103167704..3168057-354WP_186708878.1DUF559 domain-containing protein-
FRE64_RS156153168143..3168515-373Protein_3081type II toxin-antitoxin system VapC family toxin-
FRE64_RS156203168512..3168751-240WP_146297077.1type II toxin-antitoxin system Phd/YefM family antitoxin-
FRE64_RS156253168846..3169181-336WP_146297078.1DUF86 domain-containing protein-
FRE64_RS156303169178..3169480-303WP_146297397.1nucleotidyltransferase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10212.63 Da        Isoelectric Point: 10.0937

>T135398 WP_146297072.1 NZ_CP042326:3164450-3164710 [Euhalothece natronophila Z-M001]
VKFTYDPAKSKSNQSKHGINFEQAQQLWLDPLRVEIEAQSTTEPRFMIIGKIEGKYWSAIVTYRHQTIRIISVRRSRQEE
IRVYES

Download         Length: 261 bp

>T135398 NZ_CP042326:3164450-3164710 [Euhalothece natronophila Z-M001]
GTGAAATTTACATATGATCCTGCGAAAAGTAAAAGTAATCAGTCTAAACATGGAATTAACTTTGAACAAGCGCAACAACT
TTGGTTAGATCCACTTCGGGTAGAAATTGAAGCCCAATCAACCACAGAGCCTCGATTTATGATTATTGGTAAAATTGAGG
GGAAATACTGGTCTGCAATTGTTACTTATCGTCATCAAACAATTCGCATCATTTCGGTAAGAAGATCGCGTCAAGAGGAG
ATAAGAGTATATGAATCCTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8549.82 Da        Isoelectric Point: 4.6437

>AT135398 WP_146297073.1 NZ_CP042326:3164700-3164921 [Euhalothece natronophila Z-M001]
MNPEELDKKFDAGEDVMEFFDLSTLKRPELESKPINVNFPQWMIKGLDEEAKRLGVNREAVIKTWIAQKLDQK

Download         Length: 222 bp

>AT135398 NZ_CP042326:3164700-3164921 [Euhalothece natronophila Z-M001]
ATGAATCCTGAAGAATTAGATAAGAAATTTGATGCTGGTGAAGATGTAATGGAATTTTTTGATTTATCCACTCTTAAACG
CCCTGAGTTAGAGAGCAAGCCAATTAATGTTAACTTTCCGCAATGGATGATTAAAGGATTAGATGAAGAAGCAAAACGAT
TGGGAGTTAATCGAGAAGCCGTTATTAAAACTTGGATCGCGCAAAAACTAGATCAAAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References