Detailed information of TA system TA135392

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 4305743..4306737
• Replicon: chromosome
• Accession: NZ_CP042323
• Organism: Paracidovorax citrulli strain NWB SC196

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: FRC97_RS19925
• Protein ID: WP_269149363.1
• Coordinates: 4305743..4306426 (+)
• Length: 228 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: A1TRP1
• Locus tag: FRC97_RS19930
• Protein ID: WP_011796139.1
• Coordinates: 4306441..4306737 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FRC97_RS19905 (FRC97_19880)	4301077..4301415	-	339	WP_011796135.1	hypothetical protein	-
FRC97_RS19910 (FRC97_19885)	4301731..4302654	-	924	WP_228193810.1	FHA domain-containing protein	-
FRC97_RS19915 (FRC97_19890)	4302719..4304923	-	2205	WP_041828059.1	TOMM precursor leader peptide-binding protein	-
FRC97_RS19920	4305137..4305406	-	270	WP_228193812.1	hypothetical protein	-
FRC97_RS19925	4305743..4306426	+	684	WP_269149363.1	XopAJ/AvrRxo1 family type III secretion system effector zeta toxin	Toxin
FRC97_RS19930 (FRC97_19900)	4306441..4306737	+	297	WP_011796139.1	hypothetical protein	Antitoxin
FRC97_RS19935 (FRC97_19905)	4306781..4307635	-	855	WP_228193813.1	class I SAM-dependent methyltransferase	-
FRC97_RS19940 (FRC97_19910)	4307645..4308442	-	798	WP_011796141.1	BMA_0021/BMA_0022 family TOMM bacteriocin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 228 a.a.
• Molecular weight: 24279.43 Da
• Isoelectric Point: 5.1194

>T135392 WP_269149363.1 NZ_CP042323:4305743-4306426 [Paracidovorax citrulli]
IFKRSLAETPEGAKLTSAQVHAESCILADRLEDELRLQKTASGAAISMLVDKRLAGAHEIDAYIKLAQETGRKIELCDID
APLEQSLMGVLQRKPEGDAPRPPYVAVANGFSAVRGHRLDVIDKFLSNPTLGSYHLFGTTGNGSKAMVASVVNGELSIHD
PQLYEAITDPQGARAGDSGDQIIDAALIDRLTKGIDDPARAMDARTALERYAGMTWSDALAAHSSLT

Nucleotide

• Length: 684 bp

>T135392 NZ_CP042323:4305743-4306426 [Paracidovorax citrulli]
ATCTTCAAACGCTCGCTCGCAGAAACTCCAGAGGGAGCAAAACTTACCTCGGCGCAGGTACACGCCGAGTCGTGCATCCT
CGCTGACCGGCTTGAAGACGAACTCCGATTGCAGAAGACCGCGAGCGGCGCGGCGATCAGCATGCTGGTCGATAAGCGAC
TGGCTGGAGCGCACGAAATCGACGCGTACATCAAGCTGGCTCAGGAGACCGGTCGCAAAATCGAGTTGTGCGATATTGAT
GCTCCACTCGAGCAGTCACTCATGGGCGTGCTGCAGCGCAAGCCCGAAGGTGACGCCCCCCGGCCACCCTACGTTGCGGT
TGCCAACGGATTCTCGGCGGTTCGCGGGCACCGGCTCGATGTCATCGACAAGTTTCTCTCGAACCCGACCTTGGGGAGCT
ATCATCTATTCGGCACTACCGGGAATGGCAGCAAGGCGATGGTTGCCAGCGTCGTCAACGGTGAACTGAGCATTCATGAC
CCTCAGTTATACGAGGCCATTACAGATCCCCAAGGTGCCCGGGCAGGCGATAGCGGCGATCAGATCATTGACGCTGCGCT
GATCGACCGGCTGACCAAAGGTATAGACGACCCAGCGCGAGCCATGGATGCCCGCACCGCATTGGAGCGGTACGCGGGCA
TGACGTGGTCGGACGCTCTGGCCGCCCATAGTTCACTGACTTGA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11106.62 Da
• Isoelectric Point: 6.9795

>AT135392 WP_011796139.1 NZ_CP042323:4306441-4306737 [Paracidovorax citrulli]
MTGLKGADALDFHKKLKERNAALRNAELNAAKELADKNGKEPFDLVKLERLCDTSQAGRLVEGTERQAMYEYMYYVEYKN
VGTLQDFARVVTTLASWS

Nucleotide

• Length: 297 bp

>AT135392 NZ_CP042323:4306441-4306737 [Paracidovorax citrulli]
ATGACAGGCCTGAAAGGCGCAGATGCGCTCGACTTCCATAAGAAACTCAAGGAACGCAATGCTGCTTTACGCAATGCGGA
GTTGAACGCGGCGAAGGAACTGGCCGACAAAAATGGCAAGGAGCCTTTTGATCTAGTGAAACTGGAGAGGCTTTGCGATA
CCAGTCAAGCAGGCCGCCTTGTTGAAGGGACCGAACGGCAAGCCATGTACGAATACATGTACTACGTCGAGTACAAGAAT
GTTGGCACGTTGCAGGATTTCGCCCGGGTGGTGACAACACTCGCGTCCTGGTCTTAG

Structures

Antitoxin

• AlphaFold DB: A1TRP1