135384

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4514752..4514897 Replicon chromosome
Accession NZ_CP042321
Organism Klebsiella pneumoniae strain 1-16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4514759..4514861 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4514752..4514897 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FRX36_RS22305 4510284..4511717 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FRX36_RS22310 4511833..4512072 + 240 WP_002911393.1 YebV family protein -
FRX36_RS22315 4512170..4512361 + 192 WP_002911395.1 YebW family protein -
FRX36_RS22320 4512358..4513011 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
FRX36_RS22325 4513168..4514136 + 969 WP_004151446.1 VirK/YbjX family protein -
FRX36_RS22330 4514241..4514384 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4514752..4514897 + 146 - - Antitoxin
- 4514759..4514861 - 103 - - Toxin
FRX36_RS22335 4515020..4515358 - 339 WP_002911404.1 YebY family protein -
FRX36_RS22340 4515375..4516244 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
FRX36_RS22345 4516248..4516622 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FRX36_RS22350 4516735..4516965 + 231 WP_002911406.1 DNA polymerase III subunit theta -
FRX36_RS22355 4517044..4517703 + 660 WP_002911407.1 exodeoxyribonuclease X -
FRX36_RS22360 4517707..4519767 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135384 NZ_CP042321:c4514861-4514759 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT135384 NZ_CP042321:4514752-4514897 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References