Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4512908..4513053 Replicon chromosome
Accession NZ_CP042318
Organism Klebsiella pneumoniae strain 46-16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4512915..4513017 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4512908..4513053 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLM28_RS22275 4508440..4509873 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FLM28_RS22280 4509989..4510228 + 240 WP_002911393.1 YebV family protein -
FLM28_RS22285 4510326..4510517 + 192 WP_002911395.1 YebW family protein -
FLM28_RS22290 4510514..4511167 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
FLM28_RS22295 4511324..4512292 + 969 WP_004151446.1 VirK/YbjX family protein -
FLM28_RS22300 4512397..4512540 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4512908..4513053 + 146 - - Antitoxin
- 4512915..4513017 - 103 - - Toxin
FLM28_RS22305 4513176..4513514 - 339 WP_002911404.1 YebY family protein -
FLM28_RS22310 4513531..4514400 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
FLM28_RS22315 4514404..4514778 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FLM28_RS22320 4514891..4515121 + 231 WP_002911406.1 DNA polymerase III subunit theta -
FLM28_RS22325 4515200..4515859 + 660 WP_002911407.1 exodeoxyribonuclease X -
FLM28_RS22330 4515863..4517923 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135337 NZ_CP042318:c4513017-4512915 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT135337 NZ_CP042318:4512908-4513053 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References