Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4212387..4212532 Replicon chromosome
Accession NZ_CP042317
Organism Klebsiella pneumoniae strain 74-17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4212394..4212496 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4212387..4212532 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLM31_RS20455 4207919..4209352 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FLM31_RS20460 4209468..4209707 + 240 WP_002911393.1 YebV family protein -
FLM31_RS20465 4209805..4209996 + 192 WP_002911395.1 YebW family protein -
FLM31_RS20470 4209993..4210646 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
FLM31_RS20475 4210803..4211771 + 969 WP_004151446.1 VirK/YbjX family protein -
FLM31_RS20480 4211876..4212019 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4212387..4212532 + 146 - - Antitoxin
- 4212394..4212496 - 103 - - Toxin
FLM31_RS20485 4212655..4212993 - 339 WP_002911404.1 YebY family protein -
FLM31_RS20490 4213010..4213879 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
FLM31_RS20495 4213883..4214257 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FLM31_RS20500 4214370..4214600 + 231 WP_002911406.1 DNA polymerase III subunit theta -
FLM31_RS20505 4214679..4215338 + 660 WP_032435029.1 exodeoxyribonuclease X -
FLM31_RS20510 4215342..4217402 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135319 NZ_CP042317:c4212496-4212394 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT135319 NZ_CP042317:4212387-4212532 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References