Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4212387..4212532 | Replicon | chromosome |
| Accession | NZ_CP042317 | ||
| Organism | Klebsiella pneumoniae strain 74-17 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4212394..4212496 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4212387..4212532 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FLM31_RS20455 | 4207919..4209352 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| FLM31_RS20460 | 4209468..4209707 | + | 240 | WP_002911393.1 | YebV family protein | - |
| FLM31_RS20465 | 4209805..4209996 | + | 192 | WP_002911395.1 | YebW family protein | - |
| FLM31_RS20470 | 4209993..4210646 | - | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| FLM31_RS20475 | 4210803..4211771 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| FLM31_RS20480 | 4211876..4212019 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 4212387..4212532 | + | 146 | - | - | Antitoxin |
| - | 4212394..4212496 | - | 103 | - | - | Toxin |
| FLM31_RS20485 | 4212655..4212993 | - | 339 | WP_002911404.1 | YebY family protein | - |
| FLM31_RS20490 | 4213010..4213879 | - | 870 | WP_032435031.1 | copper homeostasis membrane protein CopD | - |
| FLM31_RS20495 | 4213883..4214257 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| FLM31_RS20500 | 4214370..4214600 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FLM31_RS20505 | 4214679..4215338 | + | 660 | WP_032435029.1 | exodeoxyribonuclease X | - |
| FLM31_RS20510 | 4215342..4217402 | - | 2061 | WP_004148850.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T135319 NZ_CP042317:c4212496-4212394 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT135319 NZ_CP042317:4212387-4212532 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT