Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4230601..4230746 Replicon chromosome
Accession NZ_CP042315
Organism Klebsiella pneumoniae strain 89-17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4230608..4230710 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4230601..4230746 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLM33_RS20705 4226133..4227566 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FLM33_RS20710 4227682..4227921 + 240 WP_002911393.1 YebV family protein -
FLM33_RS20715 4228019..4228210 + 192 WP_002911395.1 YebW family protein -
FLM33_RS20720 4228207..4228860 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
FLM33_RS20725 4229017..4229985 + 969 WP_004151446.1 VirK/YbjX family protein -
FLM33_RS20730 4230090..4230233 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4230601..4230746 + 146 - - Antitoxin
- 4230608..4230710 - 103 - - Toxin
FLM33_RS20735 4230869..4231207 - 339 WP_002911404.1 YebY family protein -
FLM33_RS20740 4231224..4232093 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
FLM33_RS20745 4232097..4232471 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FLM33_RS20750 4232584..4232814 + 231 WP_002911406.1 DNA polymerase III subunit theta -
FLM33_RS20755 4232893..4233552 + 660 WP_032435029.1 exodeoxyribonuclease X -
FLM33_RS20760 4233556..4235616 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135302 NZ_CP042315:c4230710-4230608 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT135302 NZ_CP042315:4230601-4230746 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References