Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4486060..4486205 Replicon chromosome
Accession NZ_CP042311
Organism Klebsiella pneumoniae strain 101-17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4486067..4486169 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4486060..4486205 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLM38_RS22175 4481592..4483025 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FLM38_RS22180 4483141..4483380 + 240 WP_002911393.1 YebV family protein -
FLM38_RS22185 4483478..4483669 + 192 WP_002911395.1 YebW family protein -
FLM38_RS22190 4483666..4484319 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
FLM38_RS22195 4484476..4485444 + 969 WP_004151446.1 VirK/YbjX family protein -
FLM38_RS22200 4485549..4485692 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4486060..4486205 + 146 - - Antitoxin
- 4486067..4486169 - 103 - - Toxin
FLM38_RS22205 4486328..4486666 - 339 WP_002911404.1 YebY family protein -
FLM38_RS22210 4486683..4487552 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
FLM38_RS22215 4487556..4487930 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FLM38_RS22220 4488043..4488273 + 231 WP_002911406.1 DNA polymerase III subunit theta -
FLM38_RS22225 4488352..4489011 + 660 WP_002911407.1 exodeoxyribonuclease X -
FLM38_RS22230 4489015..4491075 - 2061 WP_179374135.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135268 NZ_CP042311:c4486169-4486067 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT135268 NZ_CP042311:4486060-4486205 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References