Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4486858..4487003 Replicon chromosome
Accession NZ_CP042310
Organism Klebsiella pneumoniae strain 103-17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4486865..4486967 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4486858..4487003 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLM39_RS22195 4482390..4483823 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FLM39_RS22200 4483939..4484178 + 240 WP_002911393.1 YebV family protein -
FLM39_RS22205 4484276..4484467 + 192 WP_002911395.1 YebW family protein -
FLM39_RS22210 4484464..4485117 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
FLM39_RS22215 4485274..4486242 + 969 WP_004151446.1 VirK/YbjX family protein -
FLM39_RS22220 4486347..4486490 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4486858..4487003 + 146 - - Antitoxin
- 4486865..4486967 - 103 - - Toxin
FLM39_RS22225 4487126..4487464 - 339 WP_002911404.1 YebY family protein -
FLM39_RS22230 4487481..4488350 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
FLM39_RS22235 4488354..4488728 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FLM39_RS22240 4488841..4489071 + 231 WP_002911406.1 DNA polymerase III subunit theta -
FLM39_RS22245 4489150..4489809 + 660 WP_002911407.1 exodeoxyribonuclease X -
FLM39_RS22250 4489813..4491873 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135250 NZ_CP042310:c4486967-4486865 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT135250 NZ_CP042310:4486858-4487003 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References