Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4486858..4487003 | Replicon | chromosome |
| Accession | NZ_CP042310 | ||
| Organism | Klebsiella pneumoniae strain 103-17 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4486865..4486967 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4486858..4487003 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FLM39_RS22195 | 4482390..4483823 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| FLM39_RS22200 | 4483939..4484178 | + | 240 | WP_002911393.1 | YebV family protein | - |
| FLM39_RS22205 | 4484276..4484467 | + | 192 | WP_002911395.1 | YebW family protein | - |
| FLM39_RS22210 | 4484464..4485117 | - | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| FLM39_RS22215 | 4485274..4486242 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| FLM39_RS22220 | 4486347..4486490 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 4486858..4487003 | + | 146 | - | - | Antitoxin |
| - | 4486865..4486967 | - | 103 | - | - | Toxin |
| FLM39_RS22225 | 4487126..4487464 | - | 339 | WP_002911404.1 | YebY family protein | - |
| FLM39_RS22230 | 4487481..4488350 | - | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| FLM39_RS22235 | 4488354..4488728 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| FLM39_RS22240 | 4488841..4489071 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FLM39_RS22245 | 4489150..4489809 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| FLM39_RS22250 | 4489813..4491873 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T135250 NZ_CP042310:c4486967-4486865 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT135250 NZ_CP042310:4486858-4487003 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT