Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4511744..4511889 Replicon chromosome
Accession NZ_CP042309
Organism Klebsiella pneumoniae strain 109-17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4511751..4511853 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4511744..4511889 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLM40_RS22255 4507276..4508709 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FLM40_RS22260 4508825..4509064 + 240 WP_002911393.1 YebV family protein -
FLM40_RS22265 4509162..4509353 + 192 WP_002911395.1 YebW family protein -
FLM40_RS22270 4509350..4510003 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
FLM40_RS22275 4510160..4511128 + 969 WP_179373634.1 VirK/YbjX family protein -
FLM40_RS22280 4511233..4511376 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4511744..4511889 + 146 - - Antitoxin
- 4511751..4511853 - 103 - - Toxin
FLM40_RS22285 4512012..4512350 - 339 WP_002911404.1 YebY family protein -
FLM40_RS22290 4512367..4513236 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
FLM40_RS22295 4513240..4513614 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FLM40_RS22300 4513727..4513957 + 231 WP_002911406.1 DNA polymerase III subunit theta -
FLM40_RS22305 4514036..4514695 + 660 WP_002911407.1 exodeoxyribonuclease X -
FLM40_RS22310 4514699..4516759 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135232 NZ_CP042309:c4511853-4511751 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT135232 NZ_CP042309:4511744-4511889 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References