Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 501933..502483 Replicon chromosome
Accession NZ_CP042306
Organism Sphingomonas panacisoli strain HKS19

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FPZ24_RS02480 Protein ID WP_146569564.1
Coordinates 501933..502253 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FPZ24_RS02485 Protein ID WP_205012856.1
Coordinates 502250..502483 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPZ24_RS02445 497242..498147 + 906 WP_146569558.1 Hsp33 family molecular chaperone HslO -
FPZ24_RS02450 498237..498602 + 366 WP_146569559.1 hypothetical protein -
FPZ24_RS02455 498772..499461 + 690 WP_146569560.1 7-cyano-7-deazaguanine synthase QueC -
FPZ24_RS02460 499458..500099 + 642 WP_146569561.1 7-carboxy-7-deazaguanine synthase -
FPZ24_RS02465 500104..500775 - 672 WP_186728993.1 hypothetical protein -
FPZ24_RS02470 500950..501189 - 240 WP_146569562.1 hypothetical protein -
FPZ24_RS02475 501280..501936 - 657 WP_146569563.1 lipoyl(octanoyl) transferase LipB -
FPZ24_RS02480 501933..502253 - 321 WP_146569564.1 DUF5615 family PIN-like protein Toxin
FPZ24_RS02485 502250..502483 - 234 WP_205012856.1 DUF433 domain-containing protein Antitoxin
FPZ24_RS02490 502555..503376 + 822 WP_146569565.1 hypothetical protein -
FPZ24_RS02495 503373..504140 + 768 WP_146569566.1 hypothetical protein -
FPZ24_RS02500 504127..504969 - 843 WP_146569567.1 oxygen-dependent coproporphyrinogen oxidase -
FPZ24_RS02505 504966..505415 - 450 WP_146569568.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
FPZ24_RS02510 505559..506131 + 573 WP_146569569.1 ubiquinol-cytochrome c reductase iron-sulfur subunit -
FPZ24_RS02515 506146..507420 + 1275 WP_146569570.1 cytochrome b N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-74)

Antitoxin

Protein of unknown function DUF433

(9-64)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12120.04 Da        Isoelectric Point: 4.8432

>T135221 WP_146569564.1 NZ_CP042306:c502253-501933 [Sphingomonas panacisoli]
MKFLVDAQLPPALCSWLRDQGHVAMHVADIGMLAASDSEIALRAETDNAILISKDEDFLTLRLPDRFGFLWMRCGNATNR
ALLAWLDPRWEQIERLLATERLVEVR

Download         Length: 321 bp

>T135221 NZ_CP042306:c502253-501933 [Sphingomonas panacisoli]
ATGAAATTCCTGGTCGATGCGCAGTTGCCGCCCGCTCTGTGTTCCTGGCTGCGAGATCAAGGACATGTGGCCATGCATGT
CGCCGACATCGGTATGCTCGCCGCCAGCGATAGCGAGATCGCGCTCAGGGCCGAGACCGACAATGCCATCCTGATCAGCA
AGGATGAGGATTTCCTGACTCTACGGTTGCCGGATCGGTTCGGCTTTCTTTGGATGCGATGCGGAAACGCGACCAATCGC
GCATTGCTCGCATGGCTCGATCCGCGCTGGGAACAGATCGAACGCTTGCTCGCGACCGAGCGGCTCGTGGAAGTTCGATG
A

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8009.12 Da        Isoelectric Point: 4.3791

>AT135221 WP_205012856.1 NZ_CP042306:c502483-502250 [Sphingomonas panacisoli]
MTLAGFPRIAVDPQICGGRPVVAGTRVRVTDVLEMLAGGATADEITADFPYVSHEDVRAVLTYAAAQADHAVVLAAE

Download         Length: 234 bp

>AT135221 NZ_CP042306:c502483-502250 [Sphingomonas panacisoli]
ATGACGTTGGCAGGCTTTCCGCGCATCGCTGTCGATCCGCAAATCTGCGGCGGCCGTCCGGTCGTCGCGGGTACACGGGT
TCGCGTCACCGATGTACTCGAAATGCTCGCGGGTGGTGCGACGGCCGACGAGATCACGGCCGATTTCCCGTACGTGAGCC
ACGAAGACGTTCGGGCCGTCTTGACCTACGCGGCCGCCCAGGCCGACCACGCGGTGGTGCTCGCCGCCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References