Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpA-AbkA/BrnT-BrnA
Location 3540818..3541421 Replicon chromosome
Accession NZ_CP042304
Organism Devosia ginsengisoli strain Gsoil 520

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag FPZ08_RS17375 Protein ID WP_146291313.1
Coordinates 3541131..3541421 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name AbkA Uniprot ID -
Locus tag FPZ08_RS17370 Protein ID WP_146293257.1
Coordinates 3540818..3541129 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPZ08_RS17340 3536214..3537035 - 822 WP_146291301.1 tryptophan synthase subunit alpha -
FPZ08_RS17345 3537038..3538249 - 1212 WP_146291303.1 tryptophan synthase subunit beta -
FPZ08_RS17350 3538368..3539015 - 648 WP_146291305.1 phosphoribosylanthranilate isomerase -
FPZ08_RS17355 3539024..3539386 - 363 WP_146291307.1 DUF1049 domain-containing protein -
FPZ08_RS17360 3539478..3539759 - 282 WP_146291309.1 integration host factor subunit beta -
FPZ08_RS17365 3539798..3540757 - 960 WP_186767062.1 signal peptide peptidase SppA -
FPZ08_RS17370 3540818..3541129 - 312 WP_146293257.1 BrnA antitoxin family protein Antitoxin
FPZ08_RS17375 3541131..3541421 - 291 WP_146291313.1 BrnT family toxin Toxin
FPZ08_RS17380 3541468..3541971 - 504 WP_146291315.1 GNAT family N-acetyltransferase -
FPZ08_RS17385 3542068..3543771 - 1704 WP_146291317.1 30S ribosomal protein S1 -
FPZ08_RS17390 3543938..3544579 - 642 WP_146291319.1 (d)CMP kinase -
FPZ08_RS17395 3544582..3545955 - 1374 WP_146291321.1 3-phosphoshikimate 1-carboxyvinyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-87)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(32-91)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11233.57 Da        Isoelectric Point: 5.2417

>T135219 WP_146291313.1 NZ_CP042304:c3541421-3541131 [Devosia ginsengisoli]
VEYEWNEEKHQANIAKHKVYFEDAIEVFDDPNELTEPARTVSGEERLQTIGAVPFLATLLVVHTLRETIQGEVVTRIISA
RPASRKERQRYEQRER

Download         Length: 291 bp

>T135219 NZ_CP042304:c3541421-3541131 [Devosia ginsengisoli]
GTGGAGTACGAATGGAACGAAGAGAAGCACCAAGCCAATATCGCCAAGCACAAGGTGTATTTCGAGGACGCGATCGAGGT
TTTCGACGACCCCAATGAACTGACCGAGCCGGCTCGCACGGTCAGTGGGGAAGAACGGCTCCAGACTATTGGCGCGGTGC
CCTTTCTGGCCACCCTGCTGGTCGTTCATACGCTGCGAGAAACAATCCAAGGCGAAGTGGTGACGCGGATCATATCCGCC
AGGCCCGCATCTCGGAAGGAAAGACAACGCTATGAGCAACGAGAACGCTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12018.80 Da        Isoelectric Point: 10.2995

>AT135219 WP_146293257.1 NZ_CP042304:c3541129-3540818 [Devosia ginsengisoli]
MVRYTRKPLTQEQIDRLKALSERPDSEIDYSDIPPLTDEFFKNAKQGMMYRLVKQQTTLRLDADILDWFKRHAKNGKGYQ
TDINKALRAYVVAQDKKAARKAG

Download         Length: 312 bp

>AT135219 NZ_CP042304:c3541129-3540818 [Devosia ginsengisoli]
ATGGTGCGCTATACGCGCAAGCCACTGACGCAGGAGCAGATCGATCGCCTGAAGGCCCTGTCGGAAAGGCCGGACAGCGA
AATCGACTATTCCGACATACCGCCGCTGACCGATGAGTTCTTCAAAAACGCCAAGCAGGGCATGATGTATCGGCTGGTGA
AGCAGCAGACGACTTTGCGCCTCGATGCCGACATTCTCGACTGGTTCAAGCGCCATGCCAAGAATGGCAAGGGCTACCAG
ACCGACATCAACAAGGCGCTGCGTGCTTATGTCGTGGCGCAGGACAAGAAGGCGGCCCGCAAGGCCGGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References