Detailed information of TA system TA135218

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT-BrnA
• Location: 3196521..3197058
• Replicon: chromosome
• Accession: NZ_CP042304
• Organism: Devosia ginsengisoli strain Gsoil 520

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FPZ08_RS15580
• Protein ID: WP_146290850.1
• Coordinates: 3196783..3197058 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: brnA
• Uniprot ID: -
• Locus tag: FPZ08_RS15575
• Protein ID: WP_146290849.1
• Coordinates: 3196521..3196802 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FPZ08_RS15555	3191783..3193222	-	1440	WP_056233290.1	F0F1 ATP synthase subunit beta	-
FPZ08_RS15560	3193238..3194125	-	888	WP_146290847.1	F0F1 ATP synthase subunit gamma	-
FPZ08_RS15565	3194150..3195685	-	1536	WP_056256416.1	F0F1 ATP synthase subunit alpha	-
FPZ08_RS15570	3195686..3196246	-	561	WP_146290848.1	F0F1 ATP synthase subunit delta	-
FPZ08_RS15575	3196521..3196802	-	282	WP_146290849.1	BrnA antitoxin family protein	Antitoxin
FPZ08_RS15580	3196783..3197058	-	276	WP_146290850.1	BrnT family toxin	Toxin
FPZ08_RS15585	3197117..3199285	-	2169	WP_146290851.1	primosomal protein N'	-
FPZ08_RS15590	3199358..3200032	-	675	WP_146290852.1	L,D-transpeptidase	-
FPZ08_RS15595	3200095..3200412	-	318	WP_146290853.1	hypothetical protein	-
FPZ08_RS15600	3200591..3200782	+	192	WP_146290854.1	hypothetical protein	-
FPZ08_RS15605	3200843..3201835	-	993	WP_186767035.1	omptin family outer membrane protease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-82)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (17-85)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10803.11 Da
• Isoelectric Point: 6.4724

>T135218 WP_146290850.1 NZ_CP042304:c3197058-3196783 [Devosia ginsengisoli]
MEFEWDETKNRTNLVKHRVGFDLAYMFNWAGAIIEPDNRHDYGEDRFLARGYAEDGVGYSIVFTFRGPIIRIISVREFNR
KEERRYGPPQA

Nucleotide

• Length: 276 bp

>T135218 NZ_CP042304:c3197058-3196783 [Devosia ginsengisoli]
ATGGAATTCGAATGGGACGAGACCAAGAATCGGACAAATCTGGTCAAGCACCGGGTCGGGTTTGACCTAGCGTACATGTT
CAACTGGGCCGGCGCCATAATCGAACCGGACAACCGGCACGACTATGGCGAAGATCGCTTTCTGGCTCGTGGCTACGCCG
AAGACGGTGTGGGATACTCGATTGTGTTCACCTTCCGAGGCCCCATCATTCGCATAATCAGCGTCCGCGAGTTCAACCGA
AAGGAGGAAAGGCGCTATGGACCACCCCAAGCCTGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10359.85 Da
• Isoelectric Point: 10.3373

>AT135218 WP_146290849.1 NZ_CP042304:c3196802-3196521 [Devosia ginsengisoli]
MDHPKPEKRRYGVPDDENPELTEEAIRRSIPAKQFFAERGLPLPGRPKSEAPKISVSLRLDPDVVAGFKADGPGWQTRIN
AVLAESLKRKKSA

Nucleotide

• Length: 282 bp

>AT135218 NZ_CP042304:c3196802-3196521 [Devosia ginsengisoli]
ATGGACCACCCCAAGCCTGAGAAACGCCGCTACGGCGTACCCGACGACGAAAATCCCGAGCTGACCGAAGAGGCCATTCG
CCGGTCCATTCCGGCTAAGCAGTTCTTTGCCGAGCGTGGCTTGCCACTGCCCGGCCGCCCCAAATCAGAGGCGCCGAAGA
TTTCGGTCAGCCTGCGGCTCGATCCCGATGTCGTCGCCGGCTTTAAGGCGGACGGCCCCGGCTGGCAGACCCGCATCAAC
GCCGTGCTGGCCGAAAGCCTCAAGCGCAAGAAGTCGGCCTAG