Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 218618..219276 Replicon chromosome
Accession NZ_CP042304
Organism Devosia ginsengisoli strain Gsoil 520

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FPZ08_RS01155 Protein ID WP_146288283.1
Coordinates 218872..219276 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FPZ08_RS01150 Protein ID WP_146288282.1
Coordinates 218618..218875 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPZ08_RS01120 213907..214272 - 366 WP_186767155.1 TIGR02301 family protein -
FPZ08_RS01125 214286..214687 - 402 WP_186767156.1 NUDIX domain-containing protein -
FPZ08_RS01130 214754..215479 + 726 WP_146288278.1 SOS response-associated peptidase -
FPZ08_RS01135 215710..216267 - 558 WP_146288279.1 hemerythrin domain-containing protein -
FPZ08_RS01140 216412..217836 - 1425 WP_146288280.1 FAD-binding oxidoreductase -
FPZ08_RS01145 217949..218560 + 612 WP_146288281.1 histidine phosphatase family protein -
FPZ08_RS01150 218618..218875 + 258 WP_146288282.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FPZ08_RS01155 218872..219276 + 405 WP_146288283.1 type II toxin-antitoxin system VapC family toxin Toxin
FPZ08_RS01160 219325..220440 + 1116 WP_146288284.1 chorismate synthase -
FPZ08_RS01165 220444..220746 - 303 WP_146288285.1 alkylphosphonate utilization protein -
FPZ08_RS01170 220819..221564 - 746 Protein_233 TlyA family RNA methyltransferase -
FPZ08_RS01175 221561..222169 - 609 WP_146288286.1 SCO family protein -
FPZ08_RS01180 222285..222527 - 243 WP_146288287.1 exodeoxyribonuclease VII small subunit -
FPZ08_RS01185 222539..223486 - 948 WP_146288288.1 histone deacetylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-125)

Antitoxin

SpoVT-AbrB domain

(16-55)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14695.90 Da        Isoelectric Point: 7.1426

>T135215 WP_146288283.1 NZ_CP042304:218872-219276 [Devosia ginsengisoli]
VTLRAMLDTNIVSSLMRLGQGALWNKMHHFGAHHIGVSIISAAELRFGAEAKGSARLTKEVEDFLHDIAVLPFAAPADAH
YAQIRAYLKRAGTPIGGNDLFIAAHALALDLTLVTDNIREFSRVPNLRVENWLD

Download         Length: 405 bp

>T135215 NZ_CP042304:218872-219276 [Devosia ginsengisoli]
GTGACGCTTCGGGCCATGCTGGACACGAACATCGTGTCGAGCCTGATGCGCTTAGGCCAAGGCGCGCTATGGAACAAGAT
GCACCACTTTGGGGCGCATCATATCGGCGTCAGTATCATCAGCGCGGCGGAACTTCGATTTGGTGCCGAAGCGAAAGGCT
CAGCGCGGCTGACCAAGGAAGTTGAAGATTTTCTCCACGACATAGCGGTACTGCCGTTTGCCGCGCCAGCGGACGCGCAT
TACGCCCAGATCAGAGCTTATTTAAAGCGCGCGGGAACGCCGATCGGTGGTAACGACCTCTTCATCGCCGCCCACGCCCT
GGCCCTCGATCTCACTCTCGTCACCGACAATATCCGCGAGTTTTCCCGCGTACCGAATCTGCGCGTCGAGAACTGGCTTG
ATTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9393.68 Da        Isoelectric Point: 4.3286

>AT135215 WP_146288282.1 NZ_CP042304:218618-218875 [Devosia ginsengisoli]
MNQIKVDSKARTASLFRNGRNQAVRIPVEFELPGTEVTIRKDGDALVIEPKAAPKSFLDVIAKYGPVDFPDIDDSDLLPL
DEPDL

Download         Length: 258 bp

>AT135215 NZ_CP042304:218618-218875 [Devosia ginsengisoli]
ATGAACCAGATCAAGGTCGACAGCAAAGCCAGGACGGCGAGCCTGTTTCGCAATGGGCGCAATCAGGCTGTGCGTATTCC
CGTGGAGTTCGAACTGCCCGGAACCGAGGTGACCATCCGCAAGGACGGCGACGCGTTGGTTATTGAGCCAAAGGCTGCGC
CCAAGTCCTTTCTCGACGTGATTGCCAAATACGGTCCGGTCGATTTCCCCGATATCGACGACTCAGATCTGCTGCCGCTT
GATGAGCCTGACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References