Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 4629595..4630187 Replicon chromosome
Accession NZ_CP042301
Organism Nitratireductor sp. SY7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FQ775_RS22740 Protein ID WP_146299878.1
Coordinates 4629595..4629978 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FQ775_RS22745 Protein ID WP_167813126.1
Coordinates 4629975..4630187 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQ775_RS22720 4625766..4626116 + 351 WP_146299882.1 MarR family winged helix-turn-helix transcriptional regulator -
FQ775_RS22725 4626113..4626973 + 861 WP_146299881.1 C40 family peptidase -
FQ775_RS22730 4626981..4627931 - 951 WP_146299880.1 glyoxylate/hydroxypyruvate reductase A -
FQ775_RS22735 4627964..4629598 - 1635 WP_146299879.1 ABC transporter ATP-binding protein -
FQ775_RS22740 4629595..4629978 - 384 WP_146299878.1 type II toxin-antitoxin system VapC family toxin Toxin
FQ775_RS22745 4629975..4630187 - 213 WP_167813126.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FQ775_RS22750 4630272..4631423 - 1152 WP_146299876.1 ABC transporter permease -
FQ775_RS22755 4631423..4632520 - 1098 WP_146299875.1 microcin C ABC transporter permease YejB -
FQ775_RS22760 4632566..4634431 - 1866 WP_146299874.1 extracellular solute-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(1-69)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14045.99 Da        Isoelectric Point: 4.6382

>T135209 WP_146299878.1 NZ_CP042301:c4629978-4629595 [Nitratireductor sp. SY7]
MIVDASAVLAVLVREPEATDFMRAFAAESEHSISPVNYLEACMRLMKRDEDVASVDELMALSNIRLADVTADQTYLARQA
YARFGKGNHEARLNLGDCFAYALAKARGEPLLFKGDDFRKTDVEAAL

Download         Length: 384 bp

>T135209 NZ_CP042301:c4629978-4629595 [Nitratireductor sp. SY7]
ATGATCGTCGACGCTTCAGCCGTCCTTGCGGTCCTCGTGCGGGAACCGGAAGCGACCGACTTCATGCGTGCCTTTGCCGC
TGAAAGCGAACATTCCATATCGCCCGTGAACTACCTGGAAGCATGCATGAGACTGATGAAGCGCGACGAGGATGTCGCTT
CCGTCGACGAGCTCATGGCGCTCTCGAACATCAGGCTCGCTGATGTCACCGCCGACCAGACCTATCTCGCGCGCCAGGCC
TACGCGCGTTTCGGCAAGGGCAACCACGAAGCGAGGCTCAATCTCGGCGACTGCTTCGCCTATGCACTCGCCAAGGCGCG
CGGCGAGCCGCTGCTGTTCAAGGGCGACGACTTCCGCAAGACCGACGTCGAGGCCGCACTTTGA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7763.92 Da        Isoelectric Point: 7.0114

>AT135209 WP_167813126.1 NZ_CP042301:c4630187-4629975 [Nitratireductor sp. SY7]
MAKRLARQTGTTVTAAVEVALEEKLARLERSMDVEAKFQRIKRFVDALPAPPPGLTSDHSDLYDDRGLPI

Download         Length: 213 bp

>AT135209 NZ_CP042301:c4630187-4629975 [Nitratireductor sp. SY7]
ATGGCGAAGCGGCTTGCGCGGCAGACCGGGACGACCGTCACGGCGGCCGTGGAAGTGGCACTCGAGGAGAAGCTGGCTCG
CCTTGAGCGTTCCATGGACGTCGAAGCAAAGTTCCAGCGGATCAAGCGGTTCGTCGATGCCTTGCCGGCGCCTCCGCCCG
GGCTGACCAGCGATCACTCCGATCTCTACGACGATCGCGGTCTGCCGATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References