Detailed information of TA system TA135209

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 4629595..4630187
• Replicon: chromosome
• Accession: NZ_CP042301
• Organism: Nitratireductor sp. SY7

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: FQ775_RS22740
• Protein ID: WP_146299878.1
• Coordinates: 4629595..4629978 (-)
• Length: 128 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: FQ775_RS22745
• Protein ID: WP_167813126.1
• Coordinates: 4629975..4630187 (-)
• Length: 71 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FQ775_RS22720	4625766..4626116	+	351	WP_146299882.1	MarR family winged helix-turn-helix transcriptional regulator	-
FQ775_RS22725	4626113..4626973	+	861	WP_146299881.1	C40 family peptidase	-
FQ775_RS22730	4626981..4627931	-	951	WP_146299880.1	glyoxylate/hydroxypyruvate reductase A	-
FQ775_RS22735	4627964..4629598	-	1635	WP_146299879.1	ABC transporter ATP-binding protein	-
FQ775_RS22740	4629595..4629978	-	384	WP_146299878.1	type II toxin-antitoxin system VapC family toxin	Toxin
FQ775_RS22745	4629975..4630187	-	213	WP_167813126.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
FQ775_RS22750	4630272..4631423	-	1152	WP_146299876.1	ABC transporter permease	-
FQ775_RS22755	4631423..4632520	-	1098	WP_146299875.1	microcin C ABC transporter permease YejB	-
FQ775_RS22760	4632566..4634431	-	1866	WP_146299874.1	extracellular solute-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-123)

Antitoxin

• Antitoxin VapB-like (1-69)

Sequences

Toxin

Protein

• Length: 128 a.a.
• Molecular weight: 14045.99 Da
• Isoelectric Point: 4.6382

>T135209 WP_146299878.1 NZ_CP042301:c4629978-4629595 [Nitratireductor sp. SY7]
MIVDASAVLAVLVREPEATDFMRAFAAESEHSISPVNYLEACMRLMKRDEDVASVDELMALSNIRLADVTADQTYLARQA
YARFGKGNHEARLNLGDCFAYALAKARGEPLLFKGDDFRKTDVEAAL

Nucleotide

• Length: 384 bp

>T135209 NZ_CP042301:c4629978-4629595 [Nitratireductor sp. SY7]
ATGATCGTCGACGCTTCAGCCGTCCTTGCGGTCCTCGTGCGGGAACCGGAAGCGACCGACTTCATGCGTGCCTTTGCCGC
TGAAAGCGAACATTCCATATCGCCCGTGAACTACCTGGAAGCATGCATGAGACTGATGAAGCGCGACGAGGATGTCGCTT
CCGTCGACGAGCTCATGGCGCTCTCGAACATCAGGCTCGCTGATGTCACCGCCGACCAGACCTATCTCGCGCGCCAGGCC
TACGCGCGTTTCGGCAAGGGCAACCACGAAGCGAGGCTCAATCTCGGCGACTGCTTCGCCTATGCACTCGCCAAGGCGCG
CGGCGAGCCGCTGCTGTTCAAGGGCGACGACTTCCGCAAGACCGACGTCGAGGCCGCACTTTGA

Antitoxin

Protein

• Length: 71 a.a.
• Molecular weight: 7763.92 Da
• Isoelectric Point: 7.0114

>AT135209 WP_167813126.1 NZ_CP042301:c4630187-4629975 [Nitratireductor sp. SY7]
MAKRLARQTGTTVTAAVEVALEEKLARLERSMDVEAKFQRIKRFVDALPAPPPGLTSDHSDLYDDRGLPI

Nucleotide

• Length: 213 bp

>AT135209 NZ_CP042301:c4630187-4629975 [Nitratireductor sp. SY7]
ATGGCGAAGCGGCTTGCGCGGCAGACCGGGACGACCGTCACGGCGGCCGTGGAAGTGGCACTCGAGGAGAAGCTGGCTCG
CCTTGAGCGTTCCATGGACGTCGAAGCAAAGTTCCAGCGGATCAAGCGGTTCGTCGATGCCTTGCCGGCGCCTCCGCCCG
GGCTGACCAGCGATCACTCCGATCTCTACGACGATCGCGGTCTGCCGATATGA