135208

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/HTH_31(antitoxin)
Location 2415701..2416915 Replicon chromosome
Accession NZ_CP042301
Organism Nitratireductor sp. SY7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FQ775_RS11870 Protein ID WP_146300707.1
Coordinates 2415701..2416291 (-) Length 197 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FQ775_RS11875 Protein ID WP_146300708.1
Coordinates 2416340..2416915 (-) Length 192 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQ775_RS11840 2411871..2412434 + 564 WP_146300701.1 hypothetical protein -
FQ775_RS11845 2412495..2413220 - 726 WP_146300702.1 class I SAM-dependent methyltransferase -
FQ775_RS11850 2413411..2414067 + 657 WP_146300703.1 hypothetical protein -
FQ775_RS11855 2414171..2414638 + 468 WP_146300704.1 MaoC family dehydratase -
FQ775_RS11860 2414635..2415102 + 468 WP_146300705.1 MaoC family dehydratase -
FQ775_RS11865 2415182..2415679 + 498 WP_167812929.1 GNAT family N-acetyltransferase -
FQ775_RS11870 2415701..2416291 - 591 WP_146300707.1 HD domain-containing protein Toxin
FQ775_RS11875 2416340..2416915 - 576 WP_146300708.1 helix-turn-helix domain-containing protein Antitoxin
FQ775_RS11880 2416970..2417515 - 546 WP_146300709.1 adenine phosphoribosyltransferase -
FQ775_RS11885 2417615..2418469 - 855 WP_146300710.1 cytochrome c1 -
FQ775_RS11890 2418504..2419808 - 1305 WP_146300711.1 cytochrome b N-terminal domain-containing protein -
FQ775_RS11895 2419828..2420391 - 564 WP_146300712.1 ubiquinol-cytochrome c reductase iron-sulfur subunit -
FQ775_RS11900 2420745..2421089 + 345 WP_146300713.1 cupin domain-containing protein -
FQ775_RS11905 2421102..2421413 - 312 WP_146300714.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(22-174)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-63)


Sequences

Toxin        


Download         Length: 197 a.a.        Molecular weight: 21863.90 Da        Isoelectric Point: 4.8614

>T135208 WP_146300707.1 NZ_CP042301:c2416291-2415701 [Nitratireductor sp. SY7]
MESVRPADTQRLAAILSFVQAAERLKDTLRSGITAQGRAESTAEHCWRLCLLVMLFERELAGYDHLKLLKLCIVHDLGEA
ISGDVPAIHQDGDPGRAARERADLVTLCAPLPDDLRDEIVGLWDEYNQAASPEAMLVKGFDKLETMLQHVIGKNAPDFDY
VFNLSYGVAQTERHPLLRALRELVDKETTRRAEGAE

Download         Length: 591 bp

>T135208 NZ_CP042301:c2416291-2415701 [Nitratireductor sp. SY7]
ATGGAATCAGTACGGCCAGCAGACACGCAACGCCTTGCCGCCATCCTCAGTTTCGTCCAGGCGGCGGAACGGCTGAAGGA
TACGCTGAGGAGCGGGATCACAGCGCAGGGTCGCGCCGAGAGCACGGCCGAGCATTGCTGGAGGCTCTGCCTGCTCGTGA
TGCTGTTCGAGCGCGAACTGGCGGGCTACGACCATCTCAAGCTCCTGAAGCTTTGCATCGTCCACGATCTCGGCGAGGCA
ATCTCCGGTGATGTGCCGGCGATCCACCAGGATGGCGATCCGGGACGTGCGGCGCGCGAACGGGCCGACCTCGTGACGCT
GTGCGCGCCGCTGCCTGATGATTTGCGTGACGAGATTGTCGGGCTATGGGACGAATACAACCAGGCGGCGTCGCCCGAGG
CGATGCTGGTCAAGGGTTTCGACAAGCTGGAAACCATGCTGCAGCACGTGATCGGCAAGAACGCGCCCGACTTCGACTAT
GTCTTCAACCTGTCCTACGGGGTCGCGCAGACGGAAAGACATCCGCTGCTGCGGGCGCTGAGGGAACTGGTCGACAAGGA
GACGACGAGGCGGGCCGAAGGGGCGGAATGA

Antitoxin


Download         Length: 192 a.a.        Molecular weight: 21260.22 Da        Isoelectric Point: 9.0211

>AT135208 WP_146300708.1 NZ_CP042301:c2416915-2416340 [Nitratireductor sp. SY7]
MLTALPPKRDCLGPTLRRWRVINRVKQAALAEELGVSQATVSRWESGALAPDRHESRRLTRLLTARPSSSADRALLDLVR
LSSEPVHLICDLTHRLLAASPSRCRTWRVACEDLQGTSLWRFASEGIDDGEASLGDRGWYDELAPELAICTERAEFAELT
IRAGTIRYARLALSDGRFARLVRDGRRSGPA

Download         Length: 576 bp

>AT135208 NZ_CP042301:c2416915-2416340 [Nitratireductor sp. SY7]
ATGCTCACTGCCTTGCCGCCGAAACGCGACTGTCTTGGGCCGACGCTGCGCCGCTGGCGTGTGATCAACCGCGTCAAGCA
GGCGGCACTCGCCGAGGAACTCGGCGTCTCGCAGGCGACGGTGTCACGCTGGGAATCGGGCGCGCTCGCGCCGGACCGGC
ATGAAAGCCGCCGGCTGACCCGGCTCCTGACGGCACGGCCGTCATCGTCCGCCGACAGGGCGTTGCTCGACCTCGTGCGC
CTGTCGAGCGAACCTGTGCATCTGATCTGCGACCTGACGCACCGGCTGCTGGCGGCCTCGCCGTCGCGCTGCCGGACATG
GCGGGTGGCTTGCGAAGATCTTCAGGGCACCTCGCTGTGGCGCTTCGCTTCCGAAGGCATCGATGACGGCGAGGCGTCGC
TGGGTGACCGTGGCTGGTACGATGAACTGGCGCCGGAACTCGCGATCTGCACCGAGCGGGCCGAGTTCGCAGAACTGACC
ATCCGCGCCGGCACGATCCGCTATGCGCGCCTGGCACTTTCCGACGGCCGCTTCGCGCGCCTCGTGCGCGACGGACGGCG
TTCGGGGCCTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References