Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 826279..826814 Replicon chromosome
Accession NZ_CP042301
Organism Nitratireductor sp. SY7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FQ775_RS03980 Protein ID WP_146299531.1
Coordinates 826279..826554 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FQ775_RS03985 Protein ID WP_146299530.1
Coordinates 826554..826814 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQ775_RS03960 822291..822698 - 408 WP_146299535.1 helix-turn-helix domain-containing protein -
FQ775_RS03965 822765..824198 + 1434 WP_146299534.1 MFS transporter -
FQ775_RS03970 824230..825168 - 939 WP_146299533.1 N-acetyl-gamma-glutamyl-phosphate reductase -
FQ775_RS03975 825324..826274 - 951 WP_146299532.1 agmatinase -
FQ775_RS03980 826279..826554 - 276 WP_146299531.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FQ775_RS03985 826554..826814 - 261 WP_146299530.1 ribbon-helix-helix domain-containing protein Antitoxin
FQ775_RS03990 826930..827415 - 486 WP_146299529.1 30S ribosomal protein S9 -
FQ775_RS03995 827417..827878 - 462 WP_146299528.1 50S ribosomal protein L13 -
FQ775_RS04000 828108..828500 - 393 WP_146301927.1 PaaI family thioesterase -
FQ775_RS04005 828569..829432 - 864 WP_146299527.1 crotonase/enoyl-CoA hydratase family protein -
FQ775_RS04010 829564..830388 + 825 WP_146299526.1 enoyl-CoA hydratase -
FQ775_RS04015 830459..830980 + 522 WP_146299525.1 CoA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10694.29 Da        Isoelectric Point: 10.1471

>T135207 WP_146299531.1 NZ_CP042301:c826554-826279 [Nitratireductor sp. SY7]
MELFWTSKASADLVRLHDFLAAVNPRAAARTVQALAAAPQRLLEQPRIGERIQEFDPRDVRRILVGKYEMRYEISSSQIY
VLRLWHTREDR

Download         Length: 276 bp

>T135207 NZ_CP042301:c826554-826279 [Nitratireductor sp. SY7]
ATGGAACTCTTCTGGACGAGCAAGGCCTCTGCCGATCTGGTCCGGCTCCACGATTTCCTCGCCGCCGTCAACCCGCGTGC
CGCAGCGCGGACCGTGCAGGCGCTCGCTGCGGCGCCGCAACGCCTTCTCGAACAGCCGCGGATCGGTGAAAGGATACAGG
AGTTCGACCCCCGCGACGTTCGGCGTATCCTCGTCGGCAAATATGAAATGCGTTACGAGATCAGTTCATCGCAAATTTAC
GTTCTGCGCCTGTGGCACACGCGAGAGGACCGCTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9799.05 Da        Isoelectric Point: 4.3596

>AT135207 WP_146299530.1 NZ_CP042301:c826814-826554 [Nitratireductor sp. SY7]
METKVLTAHVPLPLAEKVDEMAARLERSRGWIVKQALSAWVEQEEERRRLTLEAMADVDEGRVIDHQAVQAWADSLDDDD
PLPPPR

Download         Length: 261 bp

>AT135207 NZ_CP042301:c826814-826554 [Nitratireductor sp. SY7]
ATGGAAACGAAGGTCCTGACAGCGCATGTCCCGCTGCCGCTGGCCGAGAAGGTCGATGAGATGGCGGCGCGGCTGGAGCG
GTCGCGTGGCTGGATCGTGAAGCAGGCGCTTTCGGCCTGGGTCGAACAGGAAGAAGAGCGACGACGCCTGACACTCGAGG
CAATGGCGGACGTGGATGAAGGACGCGTGATCGATCATCAGGCTGTCCAGGCCTGGGCCGACAGCCTCGACGACGACGAT
CCCCTCCCGCCACCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References