Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 1073605..1074082 Replicon chromosome
Accession NZ_CP042286
Organism Staphylococcus argenteus strain B3-25B

Toxin (Protein)


Gene name TsaT Uniprot ID A0A7U7JTG2
Locus tag FPV14_RS05120 Protein ID WP_000172413.1
Coordinates 1073605..1073793 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID A0A7U7JTE3
Locus tag FPV14_RS05125 Protein ID WP_000790107.1
Coordinates 1073822..1074082 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPV14_RS05085 1069160..1069669 + 510 WP_000727672.1 hypothetical protein -
FPV14_RS05090 1070012..1070680 + 669 WP_047556937.1 thermonuclease family protein -
FPV14_RS05095 1071044..1071244 + 201 WP_001059082.1 cold-shock protein -
FPV14_RS05100 1071857..1072069 - 213 WP_001007088.1 hypothetical protein -
FPV14_RS05105 1072130..1072414 - 285 WP_031788101.1 hypothetical protein -
FPV14_RS05110 1072503..1073072 - 570 WP_047556936.1 hypothetical protein -
FPV14_RS05120 1073605..1073793 - 189 WP_000172413.1 hypothetical protein Toxin
FPV14_RS05125 1073822..1074082 - 261 WP_000790107.1 hypothetical protein Antitoxin
FPV14_RS05130 1074422..1074625 + 204 WP_047433962.1 sterile alpha motif-like domain-containing protein -
FPV14_RS05135 1074622..1074858 - 237 WP_000368686.1 hypothetical protein -
FPV14_RS05140 1075083..1075664 + 582 WP_047556934.1 phosphoglycerate mutase family protein -
FPV14_RS05145 1075731..1076348 - 618 WP_047556932.1 LysE family transporter -
FPV14_RS05150 1076512..1077003 - 492 WP_000695603.1 GNAT family N-acetyltransferase -
FPV14_RS05155 1077410..1077832 - 423 WP_001007646.1 organic hydroperoxide resistance protein -
FPV14_RS05160 1077981..1078700 + 720 WP_047556931.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7192.89 Da        Isoelectric Point: 9.9971

>T135145 WP_000172413.1 NZ_CP042286:c1073793-1073605 [Staphylococcus argenteus]
MTLHFAILFWLALIFIVAGTFIFVLMKKTAKESKKESYLSFAVIFYIFGFAMLIYTLIFGIL

Download         Length: 189 bp

>T135145 NZ_CP042286:c1073793-1073605 [Staphylococcus argenteus]
ATGACTTTACATTTTGCAATTTTATTTTGGCTAGCATTAATTTTTATCGTTGCTGGTACATTTATATTTGTCTTAATGAA
AAAAACTGCTAAAGAATCTAAAAAAGAATCTTATTTAAGCTTCGCTGTTATTTTCTATATTTTTGGATTCGCAATGCTAA
TTTATACATTAATATTTGGAATTCTTTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 10089.30 Da        Isoelectric Point: 4.1927

>AT135145 WP_000790107.1 NZ_CP042286:c1074082-1073822 [Staphylococcus argenteus]
MKNIQLNAINLVITIIFAIFNIMITYNKDLDDLCWLLPGIIICGSILIVSFTIAMITKFWLSEILFFINIVLVLYYIYPI
FYDFIN

Download         Length: 261 bp

>AT135145 NZ_CP042286:c1074082-1073822 [Staphylococcus argenteus]
ATGAAAAACATTCAATTAAATGCTATAAATTTAGTTATAACAATCATATTTGCTATCTTTAACATTATGATTACATATAA
CAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGCATTATCATTTGCGGTTCGATACTCATTGTATCGTTTACCATTG
CAATGATTACTAAATTCTGGTTAAGTGAAATATTATTTTTTATTAACATCGTGCTCGTTCTTTATTATATTTATCCAATT
TTTTATGATTTCATTAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U7JTG2

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7JTE3

References