Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 680597..681224 Replicon chromosome
Accession NZ_CP042243
Organism Crassaminicella sp. SY095

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FQB35_RS03120 Protein ID WP_148808587.1
Coordinates 680874..681224 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag FQB35_RS03115 Protein ID WP_148808586.1
Coordinates 680597..680872 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQB35_RS03090 675893..676489 + 597 WP_168198220.1 hypothetical protein -
FQB35_RS03095 676582..676950 + 369 WP_148810744.1 holo-ACP synthase -
FQB35_RS03100 676977..678545 + 1569 WP_148808580.1 NAD(P)H-hydrate dehydratase -
FQB35_RS03105 678602..679219 + 618 WP_207707335.1 outer-membrane lipoprotein carrier protein LolA -
FQB35_RS03110 679259..680443 + 1185 WP_148808584.1 alanine racemase -
FQB35_RS03115 680597..680872 + 276 WP_148808586.1 ribbon-helix-helix protein, CopG family Antitoxin
FQB35_RS03120 680874..681224 + 351 WP_148808587.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
FQB35_RS03125 681498..682142 + 645 WP_148808589.1 DNA alkylation repair protein -
FQB35_RS03130 682265..685072 + 2808 WP_148808590.1 phosphodiester glycosidase family protein -
FQB35_RS03135 685141..685626 + 486 WP_148808592.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12789.82 Da        Isoelectric Point: 6.4714

>T135022 WP_148808587.1 NZ_CP042243:680874-681224 [Crassaminicella sp. SY095]
VIVKRGDIFYADLSPVVGSEQGGVRPVLVVQNDIGNKYSPTVIVAAITSQINKAKLPTHIEISASEYGLPKDSVVLLEQI
RTIDKKRLREKIGHSDEEMMNKVNEALLISFGLIDF

Download         Length: 351 bp

>T135022 NZ_CP042243:680874-681224 [Crassaminicella sp. SY095]
GTGATTGTAAAAAGAGGAGACATATTTTATGCAGATCTTAGTCCTGTTGTTGGTTCTGAGCAAGGTGGTGTAAGACCGGT
CCTTGTTGTTCAGAATGATATAGGAAATAAATATAGTCCTACGGTTATTGTGGCAGCAATCACCTCTCAGATTAATAAAG
CAAAGCTACCAACGCATATTGAGATTAGCGCCTCAGAATATGGGTTACCGAAGGACTCAGTGGTGTTATTAGAGCAGATT
CGAACTATTGATAAAAAGAGACTAAGAGAAAAAATAGGGCATTCTGATGAAGAAATGATGAATAAAGTAAATGAAGCTTT
ATTAATTAGCTTTGGATTAATAGATTTTTAG

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10551.36 Da        Isoelectric Point: 8.9483

>AT135022 WP_148808586.1 NZ_CP042243:680597-680872 [Crassaminicella sp. SY095]
MAESKRIMISLPNTLLQEVDNIVAMEKGNRSQFIREAMRLYIRERRKIQIRENMKKGYREMGAMNLALSEVGLDLDISAL
KSYEAKLAECE

Download         Length: 276 bp

>AT135022 NZ_CP042243:680597-680872 [Crassaminicella sp. SY095]
ATGGCTGAGTCCAAACGAATTATGATTAGTTTACCAAACACACTTTTACAAGAAGTAGATAATATTGTTGCAATGGAGAA
AGGAAACAGAAGCCAATTTATTAGAGAAGCGATGAGATTGTATATTCGTGAAAGGCGTAAGATTCAAATAAGAGAAAATA
TGAAAAAGGGTTATAGAGAAATGGGGGCTATGAATTTAGCATTATCAGAGGTAGGATTAGATTTAGATATAAGTGCACTA
AAGAGCTATGAAGCAAAGTTAGCGGAGTGTGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References