Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1764146..1764633 Replicon chromosome
Accession NZ_CP042218
Organism Luteimonas granuli strain Gr-4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FPZ22_RS08100 Protein ID WP_144892003.1
Coordinates 1764146..1764466 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FPZ22_RS08105 Protein ID WP_144894057.1
Coordinates 1764454..1764633 (-) Length 60 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPZ22_RS08075 1759201..1759809 + 609 WP_144891993.1 fatty acyl CoA synthetase -
FPZ22_RS08080 1759806..1762241 + 2436 WP_144891995.1 MMPL family transporter -
FPZ22_RS08085 1762238..1762684 + 447 WP_144891997.1 phosphotransferase -
FPZ22_RS08090 1762692..1763486 + 795 WP_144891999.1 3-oxoacyl-ACP reductase FabG -
FPZ22_RS08095 1763502..1764110 - 609 WP_144892001.1 cold shock and DUF1294 domain-containing protein -
FPZ22_RS08100 1764146..1764466 - 321 WP_144892003.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FPZ22_RS08105 1764454..1764633 - 180 WP_144894057.1 prevent-host-death family protein Antitoxin
FPZ22_RS08110 1764716..1765492 - 777 WP_144891716.1 IS21-like element helper ATPase IstB -
FPZ22_RS08115 1765489..1766502 - 1014 WP_144891714.1 IS21 family transposase -
FPZ22_RS08120 1766593..1766664 - 72 Protein_1611 type II toxin-antitoxin system prevent-host-death family antitoxin -
FPZ22_RS08125 1767604..1767918 - 315 WP_144892005.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1764716..1765492 776


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12344.18 Da        Isoelectric Point: 10.0533

>T134993 WP_144892003.1 NZ_CP042218:c1764466-1764146 [Luteimonas granuli]
MAEIVWSESVLSDLDAIADYIALEDRVAAAERVKRIFAHVEQLADHPESGSRPRELGRSRYRQVVEPPCRVFYRYDGHKV
FIPYVMRAERLLRKGRLAFRSRQAKA

Download         Length: 321 bp

>T134993 NZ_CP042218:c1764466-1764146 [Luteimonas granuli]
ATGGCTGAAATAGTCTGGTCAGAATCAGTCCTGAGCGACCTGGATGCCATTGCCGACTACATCGCGTTGGAGGACCGGGT
TGCTGCCGCGGAGCGGGTCAAGCGCATCTTTGCTCATGTCGAGCAACTCGCTGATCATCCAGAAAGCGGCAGCCGCCCAC
GGGAGCTTGGGCGGTCACGGTATCGGCAGGTCGTGGAGCCGCCCTGTCGCGTCTTCTATCGCTACGATGGGCACAAGGTG
TTCATCCCGTACGTCATGCGCGCGGAGCGTTTGCTTCGCAAGGGGCGGCTGGCGTTTCGTTCTCGACAGGCGAAGGCCTG
A

Antitoxin


Download         Length: 60 a.a.        Molecular weight: 6643.78 Da        Isoelectric Point: 10.2098

>AT134993 WP_144894057.1 NZ_CP042218:c1764633-1764454 [Luteimonas granuli]
ILITQHGLPSAYLVDVESFELMLQRMTVLEGIARGEQAIAEGRVATHAQARKRLARWLK

Download         Length: 180 bp

>AT134993 NZ_CP042218:c1764633-1764454 [Luteimonas granuli]
ATCCTCATCACGCAGCACGGCCTGCCGAGCGCGTACCTCGTGGACGTCGAGAGCTTCGAGCTCATGCTGCAGCGCATGAC
CGTGCTCGAGGGAATCGCACGCGGAGAGCAGGCGATTGCCGAGGGTCGCGTGGCAACTCATGCACAAGCCAGGAAGCGCC
TTGCCAGATGGCTGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References