Detailed information of TA system TA134993

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 1764146..1764633
• Replicon: chromosome
• Accession: NZ_CP042218
• Organism: Luteimonas granuli strain Gr-4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FPZ22_RS08100
• Protein ID: WP_144892003.1
• Coordinates: 1764146..1764466 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FPZ22_RS08105
• Protein ID: WP_144894057.1
• Coordinates: 1764454..1764633 (-)
• Length: 60 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FPZ22_RS08075	1759201..1759809	+	609	WP_144891993.1	fatty acyl CoA synthetase	-
FPZ22_RS08080	1759806..1762241	+	2436	WP_144891995.1	MMPL family transporter	-
FPZ22_RS08085	1762238..1762684	+	447	WP_144891997.1	phosphotransferase	-
FPZ22_RS08090	1762692..1763486	+	795	WP_144891999.1	3-oxoacyl-ACP reductase FabG	-
FPZ22_RS08095	1763502..1764110	-	609	WP_144892001.1	cold shock and DUF1294 domain-containing protein	-
FPZ22_RS08100	1764146..1764466	-	321	WP_144892003.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FPZ22_RS08105	1764454..1764633	-	180	WP_144894057.1	prevent-host-death family protein	Antitoxin
FPZ22_RS08110	1764716..1765492	-	777	WP_144891716.1	IS21-like element helper ATPase IstB	-
FPZ22_RS08115	1765489..1766502	-	1014	WP_144891714.1	IS21 family transposase	-
FPZ22_RS08120	1766593..1766664	-	72	Protein_1611	type II toxin-antitoxin system prevent-host-death family antitoxin	-
FPZ22_RS08125	1767604..1767918	-	315	WP_144892005.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1764716..1765492	776

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12344.18 Da
• Isoelectric Point: 10.0533

>T134993 WP_144892003.1 NZ_CP042218:c1764466-1764146 [Luteimonas granuli]
MAEIVWSESVLSDLDAIADYIALEDRVAAAERVKRIFAHVEQLADHPESGSRPRELGRSRYRQVVEPPCRVFYRYDGHKV
FIPYVMRAERLLRKGRLAFRSRQAKA

Nucleotide

• Length: 321 bp

>T134993 NZ_CP042218:c1764466-1764146 [Luteimonas granuli]
ATGGCTGAAATAGTCTGGTCAGAATCAGTCCTGAGCGACCTGGATGCCATTGCCGACTACATCGCGTTGGAGGACCGGGT
TGCTGCCGCGGAGCGGGTCAAGCGCATCTTTGCTCATGTCGAGCAACTCGCTGATCATCCAGAAAGCGGCAGCCGCCCAC
GGGAGCTTGGGCGGTCACGGTATCGGCAGGTCGTGGAGCCGCCCTGTCGCGTCTTCTATCGCTACGATGGGCACAAGGTG
TTCATCCCGTACGTCATGCGCGCGGAGCGTTTGCTTCGCAAGGGGCGGCTGGCGTTTCGTTCTCGACAGGCGAAGGCCTG
A

Antitoxin

Protein

• Length: 60 a.a.
• Molecular weight: 6643.78 Da
• Isoelectric Point: 10.2098

>AT134993 WP_144894057.1 NZ_CP042218:c1764633-1764454 [Luteimonas granuli]
ILITQHGLPSAYLVDVESFELMLQRMTVLEGIARGEQAIAEGRVATHAQARKRLARWLK

Nucleotide

• Length: 180 bp

>AT134993 NZ_CP042218:c1764633-1764454 [Luteimonas granuli]
ATCCTCATCACGCAGCACGGCCTGCCGAGCGCGTACCTCGTGGACGTCGAGAGCTTCGAGCTCATGCTGCAGCGCATGAC
CGTGCTCGAGGGAATCGCACGCGGAGAGCAGGCGATTGCCGAGGGTCGCGTGGCAACTCATGCACAAGCCAGGAAGCGCC
TTGCCAGATGGCTGAAATAG