Detailed information of TA system TA134992

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 803381..803916
• Replicon: chromosome
• Accession: NZ_CP042218
• Organism: Luteimonas granuli strain Gr-4

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: FPZ22_RS03650
• Protein ID: WP_144890447.1
• Coordinates: 803617..803916 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: FPZ22_RS03645
• Protein ID: WP_144890444.1
• Coordinates: 803381..803620 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FPZ22_RS03630	800356..801837	-	1482	WP_144890438.1	DNA polymerase Y family protein	-
FPZ22_RS03635	801845..802573	-	729	WP_168198924.1	translesion DNA synthesis-associated protein ImuA	-
FPZ22_RS03640	802570..803190	-	621	WP_144890441.1	transcriptional repressor LexA	-
FPZ22_RS03645	803381..803620	+	240	WP_144890444.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
FPZ22_RS03650	803617..803916	+	300	WP_144890447.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FPZ22_RS03655	803927..804526	-	600	WP_144890450.1	YdeI/OmpD-associated family protein	-
FPZ22_RS03660	804513..804716	-	204	WP_144890453.1	hypothetical protein	-
FPZ22_RS03665	804813..805196	-	384	WP_144890456.1	fluoride efflux transporter CrcB	-
FPZ22_RS03670	805198..806298	-	1101	WP_144890459.1	alpha/beta hydrolase	-
FPZ22_RS03675	806308..806718	-	411	WP_210412729.1	carboxymuconolactone decarboxylase family protein	-
FPZ22_RS13570	806827..807000	-	174	WP_168198925.1	GNAT family N-acetyltransferase	-
FPZ22_RS03685	807082..807395	+	314	Protein_725	DUF1153 domain-containing protein	-
FPZ22_RS03690	807392..808213	+	822	WP_210412727.1	IS3 family transposase	-
FPZ22_RS03695	808241..808471	+	231	Protein_727	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	807395..808213	818

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-92)

Antitoxin

• Antitoxin ParD (4-70)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11223.93 Da
• Isoelectric Point: 10.1386

>T134992 WP_144890447.1 NZ_CP042218:803617-803916 [Luteimonas granuli]
VSSFGLTRAARADLKSIARLTEARWGVRQRNAYLKEVDRIFHALARNPAMGRACDDILQGYRRLPHGAHVIYYRQIAGQE
VMIVRILHGAMDAEAYLDT

Nucleotide

• Length: 300 bp

>T134992 NZ_CP042218:803617-803916 [Luteimonas granuli]
GTGAGCTCTTTTGGCCTCACCAGGGCCGCCCGAGCTGATCTCAAGTCGATTGCGCGCCTCACGGAAGCCCGGTGGGGCGT
ACGACAGCGCAATGCGTATCTGAAGGAAGTCGACCGGATCTTTCATGCACTGGCCAGGAATCCCGCGATGGGGCGTGCAT
GCGACGACATTCTGCAAGGCTACCGAAGACTCCCACACGGGGCGCACGTCATCTACTACAGGCAGATCGCTGGGCAAGAA
GTCATGATCGTCCGCATCCTGCACGGTGCGATGGACGCAGAGGCGTATCTGGACACCTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8776.63 Da
• Isoelectric Point: 4.5052

>AT134992 WP_144890444.1 NZ_CP042218:803381-803620 [Luteimonas granuli]
MAKNTSVSLGDHFEEFIGSQIDSGRYGSASEVVRAGLRLLETAENRLEVLRQALREGERSGRADYSYESLVSELDAERP

Nucleotide

• Length: 240 bp

>AT134992 NZ_CP042218:803381-803620 [Luteimonas granuli]
ATGGCCAAGAACACGAGCGTCAGCCTGGGTGACCATTTCGAGGAATTCATCGGCAGCCAGATCGACAGTGGCCGATACGG
GTCGGCGAGTGAAGTCGTCCGAGCCGGGCTGCGCCTGCTCGAAACCGCCGAAAACAGGCTGGAAGTGCTTCGCCAGGCGC
TACGCGAGGGTGAGCGCAGCGGGCGTGCCGACTACAGCTACGAGTCGCTGGTTTCCGAACTGGACGCCGAGCGGCCGTGA