Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) NpoTA/ParE(toxin)
Location 439795..441070 Replicon chromosome
Accession NZ_CP042218
Organism Luteimonas granuli strain Gr-4

Toxin (Protein)


Gene name NpoT Uniprot ID -
Locus tag FPZ22_RS02010 Protein ID WP_144889797.1
Coordinates 439795..439974 (-) Length 60 a.a.

Antitoxin (Protein)


Gene name NpoA Uniprot ID -
Locus tag FPZ22_RS02015 Protein ID WP_144889800.1
Coordinates 440000..441070 (-) Length 357 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPZ22_RS01985 434968..435156 - 189 WP_144889787.1 hypothetical protein -
FPZ22_RS01990 435232..435981 - 750 WP_144889789.1 DUF1828 domain-containing protein -
FPZ22_RS01995 435987..436472 - 486 WP_144889791.1 hypothetical protein -
FPZ22_RS02000 436993..438381 - 1389 WP_144889793.1 S8 family serine peptidase -
FPZ22_RS02005 438507..439790 + 1284 WP_168198899.1 DUF445 domain-containing protein -
FPZ22_RS02010 439795..439974 - 180 WP_144889797.1 hypothetical protein Toxin
FPZ22_RS02015 440000..441070 - 1071 WP_144889800.1 SDR family oxidoreductase Antitoxin
FPZ22_RS02020 441152..443602 - 2451 WP_144889802.1 DNA ligase D -
FPZ22_RS02025 443615..444616 - 1002 WP_144889804.1 Ku protein -
FPZ22_RS02035 444929..445321 - 393 WP_144889805.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 434635..461278 26643


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 60 a.a.        Molecular weight: 6554.15 Da        Isoelectric Point: 10.4802

>T134991 WP_144889797.1 NZ_CP042218:c439974-439795 [Luteimonas granuli]
MSRGDKSAYTDKQKRKAEHIEDSEREKGRSKEDAERIAWATVNKQDGGGKKSGSGRKSS

Download         Length: 180 bp

>T134991 NZ_CP042218:c439974-439795 [Luteimonas granuli]
ATGAGCCGCGGAGACAAGTCGGCCTACACCGACAAGCAGAAGCGCAAGGCGGAGCACATCGAGGACAGTGAACGCGAGAA
GGGGCGCTCGAAGGAGGATGCCGAGCGCATCGCCTGGGCCACGGTCAACAAGCAGGACGGCGGCGGCAAGAAATCCGGTT
CCGGCCGCAAGTCTTCCTGA

Antitoxin


Download         Length: 357 a.a.        Molecular weight: 37683.65 Da        Isoelectric Point: 9.6368

>AT134991 WP_144889800.1 NZ_CP042218:c441070-440000 [Luteimonas granuli]
MATSKTGGRTTGKAGRSTSSKTSGSKAPKVGGRAEAARTVERQRDIQQKAGQAATRAKKKAPAKKQPVQAGARRQPSNPM
PAQHLAKPGNEHALELEPRFLAPGYEGSGKLEGMAAIITGGDSGIGRAVAVLFAREGADVAVLHLAEDEDAEETRRHVEA
EGRRCLVIAGDVRDPGFCNDAVRRVVKTFGRLDVLVNNAAFQQHAERLEDLSDRHLQETLQTNIAGYFHMARAALWHMEE
GASIVNTGSETGIFGSPKLLDYSATKGAIHAFTLSLASNLLDRGIRVNCVAPGPVWTPLNPADKAAPDVAAFGKDSDMGR
PAQPEEISPAFVFLASPVMSSYVNGVILPVMGGPRG

Download         Length: 1071 bp

>AT134991 NZ_CP042218:c441070-440000 [Luteimonas granuli]
ATGGCGACCAGCAAAACCGGTGGCAGGACGACGGGCAAGGCCGGCCGCAGTACGAGCAGCAAGACGTCTGGCAGCAAGGC
GCCAAAGGTCGGCGGCCGCGCGGAAGCGGCGAGGACCGTCGAGCGGCAGCGGGACATCCAGCAGAAAGCCGGACAGGCCG
CGACGCGCGCGAAGAAGAAGGCCCCGGCGAAGAAGCAGCCGGTGCAGGCCGGTGCTCGCCGTCAGCCCTCCAACCCCATG
CCCGCGCAGCATCTGGCCAAGCCCGGCAACGAGCACGCGCTGGAACTCGAACCGCGCTTCCTCGCGCCAGGCTATGAAGG
CAGCGGCAAGCTGGAAGGCATGGCCGCGATCATCACCGGCGGCGACTCCGGCATCGGCCGCGCGGTGGCGGTGCTGTTCG
CGCGCGAGGGCGCCGACGTCGCCGTGCTGCACCTCGCCGAGGACGAGGACGCGGAGGAAACCCGGCGCCACGTCGAGGCG
GAGGGCCGCCGCTGTCTGGTGATCGCCGGCGACGTGCGCGACCCCGGGTTCTGCAACGACGCGGTGCGCAGGGTGGTGAA
GACCTTCGGCCGGCTGGACGTGCTGGTCAACAACGCCGCTTTCCAGCAGCACGCCGAGCGGCTCGAGGATCTGAGCGACA
GGCACCTGCAGGAAACCCTGCAGACCAACATCGCCGGCTATTTCCACATGGCGCGCGCGGCCTTGTGGCACATGGAGGAG
GGCGCCAGCATCGTCAACACGGGCTCCGAGACGGGGATCTTCGGGAGCCCGAAACTGCTGGACTATTCCGCCACCAAGGG
CGCGATCCACGCCTTCACCCTGTCGCTCGCGAGCAACCTGCTCGACCGTGGCATCCGCGTGAACTGTGTGGCGCCAGGGC
CGGTATGGACGCCCTTGAATCCGGCGGACAAGGCCGCTCCGGACGTGGCCGCCTTCGGCAAGGACAGCGACATGGGGCGG
CCGGCACAGCCGGAGGAGATCTCGCCGGCGTTCGTCTTCCTGGCGTCACCGGTGATGTCGTCCTACGTGAACGGCGTGAT
CCTGCCCGTCATGGGCGGGCCGCGCGGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References