Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 2154800..2155420 Replicon chromosome
Accession NZ_CP042178
Organism Burkholderia sp. KBS0801

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FFI87_RS26535 Protein ID WP_138850142.1
Coordinates 2154800..2155117 (+) Length 106 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FFI87_RS26540 Protein ID WP_006750245.1
Coordinates 2155121..2155420 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFI87_RS26525 2151374..2152807 - 1434 WP_138850143.1 aldehyde dehydrogenase family protein -
FFI87_RS26530 2152836..2154476 - 1641 WP_012365545.1 acetolactate synthase large subunit -
FFI87_RS26535 2154800..2155117 + 318 WP_138850142.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FFI87_RS26540 2155121..2155420 + 300 WP_006750245.1 putative addiction module antidote protein Antitoxin
FFI87_RS26545 2155463..2156749 - 1287 WP_138850141.1 DUF445 domain-containing protein -
FFI87_RS26550 2156944..2158164 - 1221 WP_138850140.1 FAD-dependent oxidoreductase -
FFI87_RS26555 2158154..2158480 - 327 WP_012365540.1 non-heme iron oxygenase ferredoxin subunit -
FFI87_RS26560 2158497..2158985 - 489 WP_011660415.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
FFI87_RS26565 2158982..2160271 - 1290 WP_012365539.1 Rieske 2Fe-2S domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(9-102)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11898.65 Da        Isoelectric Point: 10.2348

>T134963 WP_138850142.1 NZ_CP042178:2154800-2155117 [Burkholderia sp. KBS0801]
MPYSAPTFSIRTTDVFEAWFAGLQDRVAKRRIQARIDRLSMGNRGDWKSAGSPVVEMRVDHGPGYRVYYVRRGTIWVILL
CGGDKSTQQADIRAAHAMLARLDLE

Download         Length: 318 bp

>T134963 NZ_CP042178:2154800-2155117 [Burkholderia sp. KBS0801]
ATGCCATACAGTGCACCAACATTCAGTATCCGGACCACCGACGTCTTCGAAGCGTGGTTTGCCGGCCTGCAGGATCGCGT
CGCGAAGCGCCGCATCCAGGCGCGCATCGACCGTCTGTCGATGGGCAATCGGGGCGACTGGAAATCCGCCGGCTCCCCCG
TCGTCGAAATGCGTGTCGATCACGGGCCCGGCTATCGCGTCTACTACGTCAGGCGCGGAACGATATGGGTGATCCTGCTC
TGCGGCGGCGACAAGTCGACGCAACAGGCGGACATCCGCGCCGCGCACGCGATGCTCGCGCGGCTCGATCTGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10674.11 Da        Isoelectric Point: 6.6384

>AT134963 WP_006750245.1 NZ_CP042178:2155121-2155420 [Burkholderia sp. KBS0801]
MDKIKTRPWDSAEHLKTDDDMADYFEACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKAHA

Download         Length: 300 bp

>AT134963 NZ_CP042178:2155121-2155420 [Burkholderia sp. KBS0801]
ATGGACAAGATCAAGACGCGGCCGTGGGATTCGGCCGAGCACCTGAAAACCGACGACGACATGGCCGACTACTTCGAGGC
CTGTCTGCAGGAAGCCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCGCGCGGCATGTCGC
AGGTCGCGCGCGACGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAGGCGCACGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References