Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1081467..1083232 Replicon chromosome
Accession NZ_CP042178
Organism Burkholderia sp. KBS0801

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag FFI87_RS21760 Protein ID WP_138849071.1
Coordinates 1081467..1082378 (+) Length 304 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag FFI87_RS21765 Protein ID WP_126225639.1
Coordinates 1082375..1083232 (+) Length 286 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFI87_RS21730 1076831..1077910 - 1080 WP_138849076.1 porin -
FFI87_RS21735 1078362..1078679 + 318 WP_006751284.1 non-heme iron oxygenase ferredoxin subunit -
FFI87_RS21740 1078681..1078992 + 312 WP_006758061.1 hypothetical protein -
FFI87_RS21745 1079047..1080117 + 1071 WP_138849074.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
FFI87_RS21750 1080110..1080880 + 771 WP_138849073.1 SDR family oxidoreductase -
FFI87_RS21755 1080920..1081447 + 528 WP_012366322.1 cupin domain-containing protein -
FFI87_RS21760 1081467..1082378 + 912 WP_138849071.1 alpha/beta fold hydrolase Toxin
FFI87_RS21765 1082375..1083232 + 858 WP_126225639.1 IclR family transcriptional regulator Antitoxin
FFI87_RS21770 1083229..1084026 + 798 WP_138849069.1 SDR family oxidoreductase -
FFI87_RS21775 1084019..1085686 + 1668 WP_138849067.1 thiamine pyrophosphate-binding protein -
FFI87_RS21780 1085679..1086506 + 828 WP_138849065.1 aspartate dehydrogenase -
FFI87_RS21785 1086604..1088094 + 1491 WP_138849063.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(56-284)

Antitoxin

Transcription regulator IclR, C-terminal

(144-266)


Sequences

Toxin        


Download         Length: 304 a.a.        Molecular weight: 31246.54 Da        Isoelectric Point: 6.8171

>T134959 WP_138849071.1 NZ_CP042178:1081467-1082378 [Burkholderia sp. KBS0801]
MSVIDKRERDRTAAFAALLGQFPEQRCAAGAAGTIGYREAGAGEAGAQHAGHALPVVLLHGIGSGAASWVCQLDTLGASR
RVLAWDAPGYGVSTPVHGASPTAADYAASLNAWLEALGIERCVLVGHSLGAIIAGGLCRLMPARIAGLLLISPAGGYGRA
PVETRDTRRDARLAMLDELGPAGLAEQRSGNMLSGFASEDARAWVRWNMARIVPAGYAQATHLLANADLATDLAGFRGRA
AVAVGANDAITPPAACERIAAAAQVELQVIPQAGHAGYVEAPAVYSSLIDTFCRQCDTQRGMA

Download         Length: 912 bp

>T134959 NZ_CP042178:1081467-1082378 [Burkholderia sp. KBS0801]
ATGAGTGTCATCGACAAACGTGAACGCGACCGCACCGCGGCATTCGCCGCGCTGCTCGGGCAGTTTCCCGAACAGCGCTG
CGCGGCCGGCGCGGCGGGCACGATCGGTTACCGTGAGGCTGGCGCAGGCGAGGCCGGCGCGCAGCATGCGGGCCACGCGC
TGCCCGTCGTGCTGCTGCACGGGATCGGCTCGGGCGCCGCATCGTGGGTGTGCCAGCTCGACACGCTCGGCGCGTCGCGA
CGCGTGCTCGCGTGGGATGCGCCCGGCTACGGCGTGTCGACCCCCGTGCACGGCGCGTCGCCGACCGCCGCCGATTACGC
GGCGTCGCTGAACGCGTGGCTCGAGGCACTCGGCATCGAACGCTGCGTGCTGGTCGGGCATTCGCTCGGCGCGATCATCG
CGGGTGGCTTGTGCCGCCTGATGCCCGCGCGGATCGCCGGCCTGCTGCTGATCTCGCCTGCGGGCGGCTACGGCCGCGCG
CCCGTCGAAACGCGCGACACGCGCCGCGACGCGCGCCTCGCGATGCTTGACGAACTCGGTCCGGCCGGGCTCGCCGAGCA
GCGCAGCGGCAACATGCTGTCGGGTTTCGCGAGCGAGGATGCGCGTGCGTGGGTGCGCTGGAACATGGCGCGCATCGTGC
CGGCCGGCTATGCGCAGGCCACGCATCTGCTCGCGAACGCCGATCTCGCGACCGATCTCGCCGGCTTTCGCGGCCGCGCG
GCCGTGGCCGTCGGCGCGAACGACGCGATCACGCCGCCCGCCGCGTGCGAGCGGATCGCCGCGGCCGCGCAGGTCGAGCT
GCAGGTAATTCCGCAGGCTGGCCATGCCGGCTACGTGGAAGCGCCGGCCGTCTATTCATCGCTGATCGACACGTTCTGTC
GTCAGTGCGACACGCAGCGAGGCATGGCATGA

Antitoxin


Download         Length: 286 a.a.        Molecular weight: 31371.88 Da        Isoelectric Point: 6.3573

>AT134959 WP_126225639.1 NZ_CP042178:1082375-1083232 [Burkholderia sp. KBS0801]
MSEPLQQPESDSTKADAGYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNYK
LGIAVLRLGFEYLSSLELTDLGLPVIESLRDATGFTTHIVIRDGRDVVFVAKAQCQSPVFSAIRVNVGTRLPAHATTHGH
VLMGDLSLKELRALYPEGTLSRMTSATPETVDALYEVIREDALRGYGVSNSSFERGISVVTAPVRNDTQKIVACITVTVP
RPEIDEALIADGLFDKVQRAAAELSRRLNYRSDDEHTFLKALGLR

Download         Length: 858 bp

>AT134959 NZ_CP042178:1082375-1083232 [Burkholderia sp. KBS0801]
ATGAGCGAACCGCTGCAACAACCAGAATCCGACAGCACCAAGGCCGACGCCGGCTATGTGGTGCCGGGCCTCGAACGCGG
CCTGCGGATCCTCGCCGAATTCTCGCCGCGCGAGCCGGTGCTCGGCGCGCCGGAGCTGTCCAAGCGCCTCGGCATTCCGC
GCACGACGGTGTTCCGTCTGCTGCAGACGCTCGAATCGCTCGGCTTTCTCGAGCGTGCGGACAAGGATCGCAACTACAAG
CTCGGCATCGCTGTGCTGCGGCTCGGCTTCGAATACCTGAGCTCGCTGGAGTTGACCGATCTCGGCCTGCCGGTGATCGA
GAGCCTGCGCGACGCGACCGGCTTCACGACGCACATCGTGATCCGCGACGGCCGCGACGTGGTGTTCGTCGCGAAGGCGC
AGTGCCAGTCGCCGGTGTTCAGCGCGATTCGCGTGAACGTCGGCACGCGGCTGCCCGCGCATGCGACGACGCACGGCCAC
GTGCTGATGGGCGACCTGTCGCTGAAGGAGCTGCGTGCGCTGTATCCGGAAGGCACGCTGAGCCGGATGACGAGCGCGAC
GCCGGAAACGGTCGATGCGCTTTACGAAGTGATCCGCGAGGATGCGCTGCGCGGCTACGGCGTGAGCAATTCGTCGTTCG
AGCGCGGTATCTCGGTGGTCACGGCGCCGGTGCGCAACGACACGCAGAAGATCGTCGCGTGCATCACGGTGACGGTGCCG
CGGCCGGAGATCGACGAGGCGCTGATCGCCGACGGCCTGTTCGACAAGGTGCAGCGCGCGGCGGCGGAACTGTCGCGGCG
GCTCAACTACCGCTCGGATGACGAGCACACGTTTCTGAAGGCTTTAGGACTCCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References