Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 6373235..6373797 Replicon chromosome
Accession NZ_CP042176
Organism Bradyrhizobium sp. KBS0727

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FFI89_RS29840 Protein ID WP_138835835.1
Coordinates 6373235..6373606 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FFI89_RS29845 Protein ID WP_138831073.1
Coordinates 6373606..6373797 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFI89_RS29805 6368899..6369237 - 339 WP_138831066.1 monooxygenase -
FFI89_RS29810 6369315..6369917 - 603 WP_138831067.1 hypothetical protein -
FFI89_RS29815 6370023..6370667 - 645 WP_138831068.1 dihydrofolate reductase family protein -
FFI89_RS29820 6370757..6371413 - 657 WP_138831069.1 TetR/AcrR family transcriptional regulator -
FFI89_RS29825 6371535..6372179 + 645 WP_138831070.1 glutathione S-transferase N-terminal domain-containing protein -
FFI89_RS29830 6372236..6372703 - 468 WP_138831071.1 nuclear transport factor 2 family protein -
FFI89_RS29835 6372783..6373229 - 447 WP_138831072.1 tol-pal system-associated acyl-CoA thioesterase -
FFI89_RS29840 6373235..6373606 - 372 WP_138835835.1 PIN domain-containing protein Toxin
FFI89_RS29845 6373606..6373797 - 192 WP_138831073.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FFI89_RS29850 6373862..6374776 - 915 WP_138831074.1 metallophosphoesterase -
FFI89_RS29855 6374877..6375746 - 870 WP_138831075.1 hypothetical protein -
FFI89_RS29860 6375860..6376909 - 1050 WP_138831076.1 Holliday junction branch migration DNA helicase RuvB -
FFI89_RS29865 6376906..6377523 - 618 WP_138831077.1 Holliday junction branch migration protein RuvA -
FFI89_RS29870 6377684..6378211 - 528 WP_138831078.1 crossover junction endodeoxyribonuclease RuvC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-110)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13385.64 Da        Isoelectric Point: 5.1298

>T134953 WP_138835835.1 NZ_CP042176:c6373606-6373235 [Bradyrhizobium sp. KBS0727]
MVLADTSIWIDHFRRSDLRLAQLLERGDVAMHPFVIGELLLGRVPKIAEMIDDLNTLPKATMASTDEVLKFIAVRGLPGS
GIGYVDAHLLAAVALTPETAIWTRDKRLLAAAQSLSLAAEIPE

Download         Length: 372 bp

>T134953 NZ_CP042176:c6373606-6373235 [Bradyrhizobium sp. KBS0727]
ATGGTACTGGCCGATACATCGATCTGGATCGACCATTTTCGCCGGAGTGATTTGCGGTTGGCTCAGTTGCTCGAACGTGG
CGATGTCGCCATGCACCCGTTTGTAATTGGCGAATTGCTACTTGGCCGCGTGCCCAAAATCGCCGAAATGATCGATGATC
TCAACACACTTCCGAAGGCGACCATGGCGAGTACCGACGAGGTGCTCAAGTTTATTGCTGTGCGAGGATTGCCGGGATCG
GGCATCGGCTATGTCGATGCGCACCTGTTGGCCGCTGTCGCGCTGACGCCCGAAACGGCGATCTGGACTCGTGACAAGCG
TCTGCTGGCTGCGGCGCAGTCGCTGTCTCTCGCCGCTGAAATTCCGGAGTAG

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7101.27 Da        Isoelectric Point: 11.5494

>AT134953 WP_138831073.1 NZ_CP042176:c6373797-6373606 [Bradyrhizobium sp. KBS0727]
MRTTIAIDDELFAKAQEFAGVTEKSAVIREALKAFVEREAARRLARMGGKQPNAKAPPRRRFK

Download         Length: 192 bp

>AT134953 NZ_CP042176:c6373797-6373606 [Bradyrhizobium sp. KBS0727]
ATGAGAACCACCATTGCCATCGATGACGAATTGTTTGCCAAGGCGCAGGAATTTGCCGGCGTGACGGAGAAGTCTGCCGT
CATCCGCGAAGCATTGAAGGCCTTCGTTGAGCGCGAAGCCGCACGCCGGCTCGCGCGCATGGGAGGGAAGCAGCCGAACG
CCAAGGCGCCACCGCGCCGCCGCTTCAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References