Detailed information of TA system TA134951

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 598265..598899
• Replicon: chromosome
• Accession: NZ_CP042176
• Organism: Bradyrhizobium sp. KBS0727

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: FFI89_RS02835
• Protein ID: WP_138832710.1
• Coordinates: 598495..598899 (+)
• Length: 135 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: FFI89_RS02830
• Protein ID: WP_138832708.1
• Coordinates: 598265..598498 (+)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FFI89_RS02815	593838..595565	-	1728	WP_138832702.1	hypothetical protein	-
FFI89_RS02820	596030..596869	+	840	WP_138832704.1	caspase family protein	-
FFI89_RS02825	597180..598082	-	903	WP_138832706.1	efflux RND transporter periplasmic adaptor subunit	-
FFI89_RS02830	598265..598498	+	234	WP_138832708.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
FFI89_RS02835	598495..598899	+	405	WP_138832710.1	PIN domain-containing protein	Toxin
FFI89_RS02840	598961..599389	-	429	WP_138832712.1	hypothetical protein	-
FFI89_RS02845	599376..600137	-	762	WP_138832714.1	type I restriction-modification system subunit M	-
FFI89_RS02850	600746..601705	-	960	WP_138831594.1	IS110 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-115)

Antitoxin

• SpoVT-AbrB domain (5-33)

Sequences

Toxin

Protein

• Length: 135 a.a.
• Molecular weight: 14295.15 Da
• Isoelectric Point: 4.8258

>T134951 WP_138832710.1 NZ_CP042176:598495-598899 [Bradyrhizobium sp. KBS0727]
VSAFLDTNILVYAQQTGRKAEVSQNLIAEGGTISAQVLNELVNVLRKKLGQSFGEIAAVLDDIDNALDPARPLTAQNCRS
ALALAGEHGLSFYDALIVASAIEAGCHTLYSEDMQHGRTIGALTIRNPFNEGVR

Nucleotide

• Length: 405 bp

>T134951 NZ_CP042176:598495-598899 [Bradyrhizobium sp. KBS0727]
GTGAGCGCGTTTCTCGACACCAACATTCTCGTCTACGCGCAGCAGACCGGCCGCAAGGCGGAGGTCTCACAAAATCTGAT
CGCTGAAGGCGGCACGATCAGCGCCCAGGTTCTCAACGAGCTGGTGAATGTACTGCGCAAGAAGCTGGGCCAAAGCTTCG
GTGAAATCGCCGCGGTGCTCGACGATATCGACAACGCGCTCGATCCCGCGCGTCCCCTGACCGCGCAGAATTGCCGCAGC
GCGCTTGCCCTTGCCGGCGAGCACGGCCTTTCGTTCTACGACGCGCTGATCGTCGCCTCGGCCATCGAAGCCGGCTGCCA
CACGCTCTACAGCGAGGACATGCAGCACGGCCGCACCATCGGCGCGCTGACGATCCGGAATCCGTTTAACGAAGGGGTGC
GGTGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8666.82 Da
• Isoelectric Point: 8.6362

>AT134951 WP_138832708.1 NZ_CP042176:598265-598498 [Bradyrhizobium sp. KBS0727]
MQVSKWGNSLAVRLPKALVEQLGLKEGDELNVVAASSDTLAVETKEARRLRALANIRARNWTLPADYKFDRDEANER

Nucleotide

• Length: 234 bp

>AT134951 NZ_CP042176:598265-598498 [Bradyrhizobium sp. KBS0727]
ATGCAGGTTTCCAAATGGGGTAATAGCCTCGCCGTTCGCCTGCCCAAGGCGCTGGTCGAGCAGCTCGGGCTGAAGGAAGG
CGACGAGTTGAATGTCGTCGCCGCCAGCAGCGACACCCTCGCGGTCGAGACCAAAGAGGCCAGGCGGTTGCGTGCGCTCG
CTAACATCCGCGCGCGAAACTGGACGTTGCCGGCGGACTACAAGTTCGACCGCGACGAGGCCAACGAGCGGTGA