Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 6373197..6373759 Replicon chromosome
Accession NZ_CP042175
Organism Bradyrhizobium sp. KBS0725

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FFI71_RS29845 Protein ID WP_138835835.1
Coordinates 6373197..6373568 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FFI71_RS29850 Protein ID WP_138831073.1
Coordinates 6373568..6373759 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFI71_RS29810 6368861..6369199 - 339 WP_138831066.1 monooxygenase -
FFI71_RS29815 6369277..6369879 - 603 WP_138831067.1 hypothetical protein -
FFI71_RS29820 6369985..6370629 - 645 WP_138831068.1 dihydrofolate reductase family protein -
FFI71_RS29825 6370719..6371375 - 657 WP_138831069.1 TetR/AcrR family transcriptional regulator -
FFI71_RS29830 6371497..6372141 + 645 WP_138831070.1 glutathione S-transferase N-terminal domain-containing protein -
FFI71_RS29835 6372198..6372665 - 468 WP_138831071.1 nuclear transport factor 2 family protein -
FFI71_RS29840 6372745..6373191 - 447 WP_138831072.1 tol-pal system-associated acyl-CoA thioesterase -
FFI71_RS29845 6373197..6373568 - 372 WP_138835835.1 PIN domain-containing protein Toxin
FFI71_RS29850 6373568..6373759 - 192 WP_138831073.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FFI71_RS29855 6373824..6374738 - 915 WP_138831074.1 metallophosphoesterase -
FFI71_RS29860 6374839..6375708 - 870 WP_138831075.1 hypothetical protein -
FFI71_RS29865 6375822..6376871 - 1050 WP_138831076.1 Holliday junction branch migration DNA helicase RuvB -
FFI71_RS29870 6376868..6377485 - 618 WP_138831077.1 Holliday junction branch migration protein RuvA -
FFI71_RS29875 6377646..6378173 - 528 WP_138831078.1 crossover junction endodeoxyribonuclease RuvC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-110)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13385.64 Da        Isoelectric Point: 5.1298

>T134950 WP_138835835.1 NZ_CP042175:c6373568-6373197 [Bradyrhizobium sp. KBS0725]
MVLADTSIWIDHFRRSDLRLAQLLERGDVAMHPFVIGELLLGRVPKIAEMIDDLNTLPKATMASTDEVLKFIAVRGLPGS
GIGYVDAHLLAAVALTPETAIWTRDKRLLAAAQSLSLAAEIPE

Download         Length: 372 bp

>T134950 NZ_CP042175:c6373568-6373197 [Bradyrhizobium sp. KBS0725]
ATGGTACTGGCCGATACATCGATCTGGATCGACCATTTTCGCCGGAGTGATTTGCGGTTGGCTCAGTTGCTCGAACGTGG
CGATGTCGCCATGCACCCGTTTGTAATTGGCGAATTGCTACTTGGCCGCGTGCCCAAAATCGCCGAAATGATCGATGATC
TCAACACACTTCCGAAGGCGACCATGGCGAGTACCGACGAGGTGCTCAAGTTTATTGCTGTGCGAGGATTGCCGGGATCG
GGCATCGGCTATGTCGATGCGCACCTGTTGGCCGCTGTCGCGCTGACGCCCGAAACGGCGATCTGGACTCGTGACAAGCG
TCTGCTGGCTGCGGCGCAGTCGCTGTCTCTCGCCGCTGAAATTCCGGAGTAG

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7101.27 Da        Isoelectric Point: 11.5494

>AT134950 WP_138831073.1 NZ_CP042175:c6373759-6373568 [Bradyrhizobium sp. KBS0725]
MRTTIAIDDELFAKAQEFAGVTEKSAVIREALKAFVEREAARRLARMGGKQPNAKAPPRRRFK

Download         Length: 192 bp

>AT134950 NZ_CP042175:c6373759-6373568 [Bradyrhizobium sp. KBS0725]
ATGAGAACCACCATTGCCATCGATGACGAATTGTTTGCCAAGGCGCAGGAATTTGCCGGCGTGACGGAGAAGTCTGCCGT
CATCCGCGAAGCATTGAAGGCCTTCGTTGAGCGCGAAGCCGCACGCCGGCTCGCGCGCATGGGAGGGAAGCAGCCGAACG
CCAAGGCGCCACCGCGCCGCCGCTTCAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References