Detailed information of TA system TA134947

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yeeV-yfjZ/CbtA-CbeA
• Location: 3880003..3880739
• Replicon: chromosome
• Accession: NZ_CP042173
• Organism: Yersinia sp. KBS0713

Toxin (Protein)

• Gene name: yeeV
• Uniprot ID: -
• Locus tag: FFE93_RS18420
• Protein ID: WP_138775730.1
• Coordinates: 3880368..3880739 (-)
• Length: 124 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: FFE93_RS18415
• Protein ID: WP_138775728.1
• Coordinates: 3880003..3880371 (-)
• Length: 123 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FFE93_RS18395	3875731..3875958	-	228	WP_005270906.1	helix-turn-helix domain-containing protein	-
FFE93_RS18400	3876079..3876177	-	99	Protein_3533	hypothetical protein	-
FFE93_RS18405	3876381..3877697	-	1317	WP_138775724.1	McrC family protein	-
FFE93_RS18410	3877694..3879757	-	2064	WP_138775726.1	McrB family protein	-
FFE93_RS18415	3880003..3880371	-	369	WP_138775728.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
FFE93_RS18420	3880368..3880739	-	372	WP_138775730.1	TA system toxin CbtA family protein	Toxin
FFE93_RS18425	3880831..3881262	-	432	WP_050120324.1	antirestriction protein	-
FFE93_RS18430	3881622..3882443	-	822	WP_138775732.1	DUF945 domain-containing protein	-
FFE93_RS18435	3882518..3882964	-	447	WP_138775734.1	hypothetical protein	-
FFE93_RS21600	3883000..3883173	-	174	WP_019081230.1	hypothetical protein	-
FFE93_RS18440	3883187..3884455	-	1269	WP_138775736.1	hypothetical protein	-
FFE93_RS18445	3884475..3884912	-	438	WP_138775738.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (13-101)

Antitoxin

• Antitoxin CbeA (10-108)

Sequences

Toxin

Protein

• Length: 124 a.a.
• Molecular weight: 13495.51 Da
• Isoelectric Point: 6.8768

>T134947 WP_138775730.1 NZ_CP042173:c3880739-3880368 [Yersinia sp. KBS0713]
MKPNPTTAGALPVPAIYQQLLAFLLDHHYGLSLNDTPYHDEQVIAQQIEQGISVGDTINALVDKYVLVRIGRAGFSALAQ
DPMLSKGDIVRARQAAGLWRAHFPPTLLYPTESLNPIPQRPLT

Nucleotide

• Length: 372 bp

>T134947 NZ_CP042173:c3880739-3880368 [Yersinia sp. KBS0713]
ATGAAACCAAACCCCACAACAGCGGGTGCATTACCCGTGCCTGCTATTTATCAACAACTGCTCGCTTTCCTGCTGGATCA
CCACTACGGCCTGAGCCTCAACGATACGCCCTATCACGATGAACAGGTGATTGCACAGCAGATAGAACAAGGGATTTCAG
TGGGCGATACCATTAATGCATTGGTTGATAAATATGTATTAGTGCGAATTGGTCGTGCCGGGTTCAGCGCACTGGCGCAA
GACCCGATGTTAAGCAAAGGCGATATCGTGCGGGCTCGCCAGGCTGCGGGTCTGTGGCGTGCTCATTTCCCGCCCACCTT
GCTGTACCCAACCGAATCCCTCAATCCTATTCCACAGAGACCGTTAACATGA

Antitoxin

Protein

• Length: 123 a.a.
• Molecular weight: 13285.04 Da
• Isoelectric Point: 6.2091

>AT134947 WP_138775728.1 NZ_CP042173:c3880371-3880003 [Yersinia sp. KBS0713]
MNNHMTTSPTWGLKRDITPRLGARLVQEGTHLHFLSDRAHIVGTFSLEATQALDAAFPALITKLESQLLSGALDPRRQQG
ITVRHGEFVCEADTLGSHGYVYIAVYQELSLLLSEGGGPTDV

Nucleotide

• Length: 369 bp

>AT134947 NZ_CP042173:c3880371-3880003 [Yersinia sp. KBS0713]
ATGAATAACCACATGACTACTTCCCCAACATGGGGCCTGAAACGTGATATTACGCCGCGGTTGGGAGCCAGACTAGTTCA
GGAGGGAACGCATCTGCATTTTCTGAGCGACAGAGCCCACATTGTCGGCACCTTTTCCCTTGAAGCCACTCAGGCTCTTG
ATGCAGCGTTTCCCGCGCTGATAACCAAACTGGAATCGCAACTGCTGTCCGGGGCGCTGGATCCACGCCGCCAGCAAGGC
ATTACGGTTCGGCATGGAGAATTTGTCTGTGAAGCGGATACGCTGGGCAGTCACGGTTATGTCTATATCGCGGTGTATCA
GGAACTGTCTTTGTTACTTTCAGAAGGCGGTGGGCCAACTGATGTTTAA