Detailed information of TA system TA134936

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /COG5642-COG5654
• Location: 2107142..2108126
• Replicon: chromosome
• Accession: NZ_CP042173
• Organism: Yersinia sp. KBS0713

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FFE93_RS09885
• Protein ID: WP_005270456.1
• Coordinates: 2107142..2107600 (-)
• Length: 153 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FFE93_RS09890
• Protein ID: WP_005270459.1
• Coordinates: 2107680..2108126 (-)
• Length: 149 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FFE93_RS09855	2103028..2103693	+	666	WP_005270436.1	phage shock protein PspA	-
FFE93_RS09860	2103793..2104020	+	228	WP_032896218.1	envelope stress response membrane protein PspB	-
FFE93_RS09865	2104020..2104394	+	375	WP_005270439.1	envelope stress response membrane protein PspC	-
FFE93_RS09870	2104439..2104678	+	240	WP_032896220.1	phage shock protein PspD	-
FFE93_RS09875	2104659..2106056	+	1398	WP_032896223.1	YcjX family protein	-
FFE93_RS09880	2106053..2107114	+	1062	WP_032896225.1	YcjF family protein	-
FFE93_RS09885	2107142..2107600	-	459	WP_005270456.1	RES family NAD+ phosphorylase	Toxin
FFE93_RS09890	2107680..2108126	-	447	WP_005270459.1	DUF2384 domain-containing protein	Antitoxin
FFE93_RS09895	2108445..2110022	+	1578	WP_032896227.1	transcriptional regulator TyrR	-
FFE93_RS09900	2110134..2110637	-	504	WP_005270467.1	thiol peroxidase	-
FFE93_RS09905	2110791..2111762	+	972	WP_138775077.1	L-Ala-D/L-Glu epimerase	-
FFE93_RS09910	2111759..2112466	-	708	WP_032896232.1	murein tripeptide amidase MpaA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-146)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (94-145)

Sequences

Toxin

Protein

• Length: 153 a.a.
• Molecular weight: 17256.77 Da
• Isoelectric Point: 5.5398

>T134936 WP_005270456.1 NZ_CP042173:c2107600-2107142 [Yersinia sp. KBS0713]
MMLYRIVMRRYLASTWTGYGAEIYGGRWNHKGHAALYLASSVSLAMLETLVHIQDSSTLSEFELFQIEIDDSHIMLLQRP
DWPTDWRSDPAPATTMDLGTEWLESASSVGLLVPSTLVPSENNMLVNPRHKEFPLCLNSVKPLSFSFDPRLK

Nucleotide

• Length: 459 bp

>T134936 NZ_CP042173:c2107600-2107142 [Yersinia sp. KBS0713]
ATGATGCTCTATCGCATTGTGATGCGCCGTTATCTTGCATCAACCTGGACCGGCTATGGCGCTGAAATCTATGGTGGGCG
CTGGAATCATAAAGGCCACGCGGCTCTCTATCTGGCCAGCAGTGTGTCATTAGCCATGCTGGAAACACTGGTGCATATTC
AGGACAGCTCAACCCTCAGCGAATTTGAACTATTTCAAATCGAGATTGATGACAGCCATATCATGCTGTTGCAGCGCCCA
GATTGGCCCACTGACTGGCGTAGCGACCCCGCACCGGCCACCACCATGGATCTTGGCACTGAGTGGCTGGAATCAGCATC
CTCAGTTGGATTACTGGTTCCATCCACATTAGTGCCGTCGGAAAACAACATGTTAGTCAATCCGCGCCACAAAGAGTTTC
CACTCTGCTTGAACAGCGTCAAACCCCTGTCGTTCTCCTTTGATCCACGGTTGAAGTAG

Antitoxin

Protein

• Length: 149 a.a.
• Molecular weight: 16204.59 Da
• Isoelectric Point: 8.1348

>AT134936 WP_005270459.1 NZ_CP042173:c2108126-2107680 [Yersinia sp. KBS0713]
MRAYHPTPASKTGALWREIGLPASRGTVLVDSIKLGFSVDVIDSIHLWASMPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKGKAITWMSTPIKGLGHHSPDSLLETETGALEVCDLIGRLEHGVFS

Nucleotide

• Length: 447 bp

>AT134936 NZ_CP042173:c2108126-2107680 [Yersinia sp. KBS0713]
ATGAGAGCATATCACCCAACACCTGCGAGCAAAACTGGCGCACTCTGGCGTGAGATTGGTTTGCCCGCCAGCCGTGGCAC
CGTTTTGGTTGACAGCATTAAGTTGGGGTTTTCTGTTGATGTCATCGACAGTATTCACCTTTGGGCCTCCATGCCTAAAG
CTGAAATATTACGTGCAACGGGGATCCCCAGCCGTAGTCTAACCCGTAGACGTACCCATGATGGCCGTTTTACGCCGGAA
GAGAGTGAGCGAATTGCACGTTTCGTCCGCGTGATGGATGCGGCAGTCGATCTTTTTGGCGGCGATAAGGGCAAGGCCAT
CACCTGGATGTCAACGCCAATTAAGGGGTTGGGGCATCACAGCCCAGACTCTTTACTCGAGACAGAAACCGGCGCATTGG
AAGTTTGTGACCTCATTGGGCGGTTGGAGCACGGCGTATTTTCCTAA