Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 658167..658762 Replicon chromosome
Accession NZ_CP042166
Organism Burkholderia contaminans strain ZCC

Toxin (Protein)


Gene name chpB Uniprot ID A0A1E3FP25
Locus tag FPQ37_RS36450 Protein ID WP_039362634.1
Coordinates 658412..658762 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID A0A0G3Z282
Locus tag FPQ37_RS36445 Protein ID WP_039362633.1
Coordinates 658167..658418 (+) Length 84 a.a.

Genomic Context

FPQ37_RS36430FPQ37_RS36435FPQ37_RS36445FPQ37_RS36450FPQ37_RS36440FPQ37_RS36455FPQ37_RS36460
Location: 653448..654125 (678 bp)
Type: Others
Protein ID: WP_039362629.1
Location: 654122..655582 (1461 bp)
Type: Others
Protein ID: WP_039362631.1
Location: 658167..658418 (252 bp)
Type: Antitoxin
Protein ID: WP_039362633.1
Location: 658412..658762 (351 bp)
Type: Toxin
Protein ID: WP_039362634.1
Location: 655814..657634 (1821 bp)
Type: Others
Protein ID: WP_046197074.1
Location: 658886..660415 (1530 bp)
Type: Others
Protein ID: WP_039362750.1
Location: 660447..661907 (1461 bp)
Type: Others
Protein ID: WP_039362635.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FPQ37_RS36430653448..654125+678WP_039362629.1heavy metal response regulator transcription factor-
FPQ37_RS36435654122..655582+1461WP_039362631.1heavy metal sensor histidine kinase-
FPQ37_RS36440655814..657634-1821WP_046197074.1asparagine synthase (glutamine-hydrolyzing)-
FPQ37_RS36445658167..658418+252WP_039362633.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
FPQ37_RS36450658412..658762+351WP_039362634.1type II toxin-antitoxin system ChpB family toxinToxin
FPQ37_RS36455658886..660415-1530WP_039362750.1efflux transporter outer membrane subunit-
FPQ37_RS36460660447..661907-1461WP_039362635.1efflux RND transporter periplasmic adaptor subunit-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--646730..65876212032


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12403.30 Da        Isoelectric Point: 10.0752

>T134927 WP_039362634.1 NZ_CP042166:658412-658762 [Burkholderia contaminans]
MVRRVKFERGDIVRVSLNPTVGKEQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARYAGFAVPLSGSGTETQGVALV
NMVRTLDLQARGARKVERAPSEVIEDALARLQTILE

Download         Length: 351 bp

>T134927 NZ_CP042166:658412-658762 [Burkholderia contaminans]
ATGGTGAGGCGCGTCAAGTTCGAGAGGGGCGATATTGTGCGCGTTAGCCTGAACCCGACCGTGGGCAAGGAGCAACAAGG
GGATTTTCGCCCCGCGCTCGTTTTGTCGCCTGCTGCGTTCAATGCGCTTGGCGTGGCGCTCGTCGCGCCGATTACGCAGG
GCGGCGAATTCGCGCGATACGCGGGATTCGCTGTGCCCCTCTCGGGTTCGGGCACTGAAACGCAGGGCGTGGCTCTTGTG
AACATGGTTCGCACGCTCGATCTTCAGGCGCGTGGCGCACGTAAGGTCGAGCGCGCTCCGTCCGAAGTGATCGAAGATGC
GCTCGCGCGTCTTCAGACCATTCTCGAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8948.19 Da        Isoelectric Point: 4.7204

>AT134927 WP_039362633.1 NZ_CP042166:658167-658418 [Burkholderia contaminans]
MELKIQKWGNSAAVRLPAVLLEQIDASVGSSLNADVRPDGVLLSPARRKYSLDELIAQCDPKAPEPADLAAWGESKPVGH
EAW

Download         Length: 252 bp

>AT134927 NZ_CP042166:658167-658418 [Burkholderia contaminans]
ATGGAACTCAAAATTCAGAAGTGGGGCAACAGCGCCGCAGTCCGGCTTCCGGCCGTGTTGCTTGAGCAAATCGACGCGTC
GGTAGGTAGCTCGCTGAACGCCGATGTGCGCCCCGATGGTGTGTTGCTTTCGCCAGCCCGGCGCAAGTATTCACTGGATG
AACTGATTGCGCAGTGCGATCCGAAGGCCCCGGAACCCGCCGACCTTGCCGCGTGGGGCGAATCCAAGCCGGTGGGGCAT
GAAGCATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A1E3FP25

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A0G3Z282

References