Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1851044..1851574 Replicon chromosome
Accession NZ_CP042164
Organism Burkholderia contaminans strain ZCC

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FPQ37_RS08755 Protein ID WP_076841743.1
Coordinates 1851311..1851574 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FPQ37_RS08750 Protein ID WP_076841742.1
Coordinates 1851044..1851289 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPQ37_RS08720 1846111..1847127 + 1017 WP_039358635.1 acetyltransferase -
FPQ37_RS08725 1847377..1847643 + 267 WP_046196769.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
FPQ37_RS08730 1847640..1848056 + 417 Protein_1634 type II toxin-antitoxin system VapC family toxin -
FPQ37_RS08735 1848105..1848344 - 240 Protein_1635 nucleotidyltransferase -
FPQ37_RS08740 1848358..1849425 - 1068 WP_039358630.1 hypothetical protein -
FPQ37_RS08745 1849766..1850927 + 1162 Protein_1637 amidohydrolase -
FPQ37_RS08750 1851044..1851289 + 246 WP_076841742.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
FPQ37_RS08755 1851311..1851574 + 264 WP_076841743.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FPQ37_RS08760 1851645..1852946 - 1302 Protein_1640 cobyrinate a,c-diamide synthase -
FPQ37_RS08765 1852949..1853551 - 603 WP_039358616.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
FPQ37_RS08770 1853589..1853966 - 378 WP_039358613.1 cobalamin biosynthesis protein -
FPQ37_RS08775 1853963..1854712 - 750 WP_039358610.1 uroporphyrinogen-III C-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10242.66 Da        Isoelectric Point: 6.0735

>T134921 WP_076841743.1 NZ_CP042164:1851311-1851574 [Burkholderia contaminans]
MAELDLEDIWRDTVGRGSLKQTDLYHRDLIGTMEALARGEKVGRTCIVRDGYFRYAVGSHVVFYRETEYTIDLIRVLHQR
MDIEQHL

Download         Length: 264 bp

>T134921 NZ_CP042164:1851311-1851574 [Burkholderia contaminans]
CTGGCCGAACTCGATCTCGAAGACATTTGGCGCGATACCGTCGGGCGTGGGTCGCTCAAGCAAACCGACCTTTACCACCG
CGATCTGATCGGAACCATGGAAGCGCTGGCGCGCGGTGAAAAGGTCGGCCGGACTTGCATTGTTCGCGATGGATATTTCC
GGTACGCCGTGGGCTCCCACGTCGTGTTCTATCGTGAAACGGAATACACGATCGATTTGATTCGGGTCCTGCATCAACGC
ATGGACATCGAACAACATCTGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9021.01 Da        Isoelectric Point: 5.6864

>AT134921 WP_076841742.1 NZ_CP042164:1851044-1851289 [Burkholderia contaminans]
MSQNASVSRRDHFAELVDTQVQSEQYGSASDVERTGLRLLESRDMQVRALQEALKAGEVSGALRPFDREAFLARMRAAHD
G

Download         Length: 246 bp

>AT134921 NZ_CP042164:1851044-1851289 [Burkholderia contaminans]
ATGTCGCAAAACGCATCCGTTTCCCGGCGCGACCACTTTGCCGAACTCGTCGATACCCAAGTGCAATCGGAACAATACGG
TTCCGCAAGCGACGTCGAACGAACCGGTTTGCGGCTTCTCGAATCACGCGACATGCAGGTGCGCGCGTTGCAGGAAGCGT
TGAAGGCCGGGGAGGTATCGGGAGCACTCAGGCCATTCGACCGCGAGGCCTTCCTGGCCCGCATGCGGGCCGCGCATGAC
GGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References