Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2769886..2770157 Replicon chromosome
Accession NZ_CP041996
Organism Escherichia coli strain AR Bank #0349

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2769924..2770026 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2769886..2770157 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FN958_RS13260 2767043..2768482 + 1440 WP_024179479.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FN958_RS13265 2768600..2768836 + 237 WP_001295499.1 DUF1480 family protein -
FN958_RS13270 2768941..2769132 + 192 WP_001296140.1 YebW family protein -
FN958_RS13275 2769133..2769789 - 657 WP_000812752.1 protein-serine/threonine phosphatase -
- 2769886..2770157 + 272 - - Antitoxin
- 2769924..2770026 - 103 - - Toxin
FN958_RS13280 2770185..2770526 - 342 WP_000976484.1 YebY family protein -
FN958_RS13285 2770539..2771411 - 873 WP_000879323.1 copper homeostasis membrane protein CopD -
FN958_RS13290 2771415..2771789 - 375 WP_000168737.1 CopC domain-containing protein YobA -
FN958_RS13295 2771928..2772158 + 231 WP_000916763.1 DNA polymerase III subunit theta -
FN958_RS13300 2772260..2772916 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
FN958_RS13305 2772940..2773602 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T134789 NZ_CP041996:c2770026-2769924 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT134789 NZ_CP041996:2769886-2770157 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References