Detailed information of TA system TA134767

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 1970524..1971151
• Replicon: chromosome
• Accession: NZ_CP041971
• Organism: Acinetobacter gyllenbergii strain NCCP 16015

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A857I7R6
• Locus tag: FPL18_RS09225
• Protein ID: WP_004657714.1
• Coordinates: 1970762..1971151 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: FPL18_RS09220
• Protein ID: WP_171066091.1
• Coordinates: 1970524..1970769 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FPL18_RS09195	1965639..1966004	+	366	WP_004641032.1	50S ribosomal protein L17	-
FPL18_RS09200	1966163..1966683	+	521	Protein_1782	GNAT family N-acetyltransferase	-
FPL18_RS09205	1966990..1968480	+	1491	WP_004657704.1	NAD(P)/FAD-dependent oxidoreductase	-
FPL18_RS09210	1968606..1969106	+	501	WP_159414210.1	DUF2059 domain-containing protein	-
FPL18_RS09215	1969151..1970323	-	1173	WP_004657709.1	acyl-CoA dehydrogenase family protein	-
FPL18_RS09220	1970524..1970769	+	246	WP_171066091.1	succinate dehydrogenase assembly factor 2	Antitoxin
FPL18_RS09225	1970762..1971151	+	390	WP_004657714.1	hypothetical protein	Toxin
FPL18_RS09230	1971359..1971565	+	207	WP_070076003.1	hypothetical protein	-
FPL18_RS09235	1971925..1973064	+	1140	WP_004657723.1	hypothetical protein	-
FPL18_RS09240	1973141..1973710	+	570	WP_004657724.1	rhombosortase	-
FPL18_RS09245	1973866..1976076	+	2211	WP_101235346.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-126)

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15724.63 Da
• Isoelectric Point: 10.1054

>T134767 WP_004657714.1 NZ_CP041971:1970762-1971151 [Acinetobacter gyllenbergii]
MANSAFELQYSRFALVLQLLLFLFIVGLVYSLVTFWWWLLSFAMMTIAWLSFLRQPQIRRFEYLDHQDCSFEFSDPTLKI
QRRQIVKILDHQLYIALYFSHKKHKPCIIWWDQLSHSQWKKLKVHAKLS

Nucleotide

• Length: 390 bp

>T134767 NZ_CP041971:1970762-1971151 [Acinetobacter gyllenbergii]
ATGGCTAATTCTGCTTTTGAGTTGCAATACAGTCGTTTTGCGCTTGTACTGCAACTCTTGTTGTTTCTCTTTATTGTGGG
CTTAGTTTATTCATTAGTTACATTTTGGTGGTGGTTACTGAGCTTTGCGATGATGACCATCGCATGGTTATCGTTTTTGC
GGCAACCCCAAATTAGGCGTTTTGAATACTTAGATCACCAAGACTGTTCATTCGAATTTTCTGATCCGACCTTGAAAATT
CAGCGTAGACAGATTGTCAAAATATTGGATCACCAGCTCTATATTGCCCTCTATTTTTCTCATAAAAAGCATAAACCCTG
CATTATTTGGTGGGATCAATTGTCACATTCGCAATGGAAAAAGCTAAAAGTACATGCAAAACTAAGCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9679.13 Da
• Isoelectric Point: 4.7010

>AT134767 WP_171066091.1 NZ_CP041971:1970524-1970769 [Acinetobacter gyllenbergii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLTADAAEKALFAELVDQEDPDLLDWFMEVGEPPRIELKEFILKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT134767 NZ_CP041971:1970524-1970769 [Acinetobacter gyllenbergii]
ATGACACTGGAAGAGCGTAAGGTTGTATATCGTGCCCGTCGTGGTTTAAAAGAAATCGATGTGTATTTCGACCCGTACGT
TAAAAACTACTATTTAACTGCTGATGCTGCTGAAAAAGCCTTATTTGCCGAGCTCGTCGATCAAGAAGACCCAGATTTAT
TGGATTGGTTTATGGAAGTGGGTGAGCCACCGCGTATTGAGTTAAAAGAGTTTATTCTCAAACTCAAACATTATGTGCAT
GGCTAA

Structures

Toxin

• AlphaFold DB: A0A857I7R6