Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1396848..1397497 Replicon chromosome
Accession NZ_CP041971
Organism Acinetobacter gyllenbergii strain NCCP 16015

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FPL18_RS06460 Protein ID WP_159413967.1
Coordinates 1396848..1397267 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FPL18_RS06465 Protein ID WP_101236761.1
Coordinates 1397267..1397497 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPL18_RS06425 1392485..1393189 - 705 WP_004656662.1 DUF1003 domain-containing protein -
FPL18_RS06430 1393309..1393548 - 240 WP_159413965.1 hypothetical protein -
FPL18_RS06435 1393683..1394384 - 702 WP_159413966.1 hypothetical protein -
FPL18_RS06440 1394510..1395208 - 699 WP_101236760.1 hypothetical protein -
FPL18_RS06445 1395268..1395792 - 525 WP_070076681.1 GNAT family N-acetyltransferase -
FPL18_RS06450 1395871..1396446 - 576 WP_070076682.1 DUF4126 domain-containing protein -
FPL18_RS06455 1396574..1396717 - 144 WP_004637424.1 zinc ribbon-containing protein -
FPL18_RS06460 1396848..1397267 - 420 WP_159413967.1 type II toxin-antitoxin system VapC family toxin Toxin
FPL18_RS06465 1397267..1397497 - 231 WP_101236761.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FPL18_RS06470 1397855..1398106 - 252 WP_159413968.1 hypothetical protein -
FPL18_RS06475 1398470..1401076 - 2607 WP_159413969.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
FPL18_RS06480 1401076..1402233 - 1158 WP_005200876.1 2-methylcitrate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-128)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15960.09 Da        Isoelectric Point: 5.9848

>T134766 WP_159413967.1 NZ_CP041971:c1397267-1396848 [Acinetobacter gyllenbergii]
MQTQYLLDTNICIYISKHQPENVRQHFEKHLPNRNILISVVTLGELRFGAEKSQSKEKALKVIDEFTSMIQVAELDEDVA
DHYAQIRQALSSQGQIIGSNDLWLAAHARANNWVMVTNNEKEFLRVDGLRVENWVSTPL

Download         Length: 420 bp

>T134766 NZ_CP041971:c1397267-1396848 [Acinetobacter gyllenbergii]
ATGCAGACACAATATTTATTGGATACCAATATTTGTATCTATATCAGCAAACATCAGCCTGAAAATGTCCGTCAGCATTT
TGAAAAGCATCTTCCCAATCGAAATATTTTAATCTCGGTGGTTACCTTAGGTGAACTACGTTTTGGCGCTGAAAAAAGTC
AAAGTAAAGAAAAAGCATTAAAAGTCATTGATGAGTTTACATCAATGATTCAAGTGGCTGAATTAGATGAAGATGTTGCG
GATCATTATGCGCAAATACGTCAAGCGCTTTCTTCTCAAGGTCAGATCATTGGATCTAATGATTTATGGCTTGCAGCGCA
TGCCAGAGCAAATAATTGGGTGATGGTCACCAATAATGAAAAAGAGTTTTTACGTGTTGATGGACTGCGTGTGGAGAATT
GGGTGTCAACTCCCTTATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 9111.29 Da        Isoelectric Point: 4.4519

>AT134766 WP_101236761.1 NZ_CP041971:c1397497-1397267 [Acinetobacter gyllenbergii]
MSTAKVFMTGRSQAIRLPKEFRFESTEVEIFRRGDEVILREKPITAERLFNVLAQMPDDFYEEERVDQPPQEREEF

Download         Length: 231 bp

>AT134766 NZ_CP041971:c1397497-1397267 [Acinetobacter gyllenbergii]
ATGTCTACCGCAAAAGTTTTTATGACCGGCCGTAGTCAAGCGATTCGCTTACCGAAAGAGTTTCGATTTGAAAGCACAGA
AGTTGAAATATTTCGCCGTGGCGATGAAGTGATCCTACGTGAAAAACCAATCACTGCAGAACGCTTATTTAATGTATTAG
CACAAATGCCAGATGATTTTTATGAAGAAGAAAGAGTGGATCAACCACCGCAAGAACGAGAAGAGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References