Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4803220..4803581 Replicon chromosome
Accession NZ_CP041967
Organism Xanthomonas citri pv. glycines strain K2

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag FPL05_RS22165 Protein ID WP_005914328.1
Coordinates 4803220..4803354 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag FPL05_RS22170 Protein ID WP_003486606.1
Coordinates 4803429..4803581 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPL05_RS22145 4798371..4800062 - 1692 WP_016850771.1 M20/M25/M40 family metallo-hydrolase -
FPL05_RS22150 4800254..4801288 - 1035 WP_016850772.1 MBL fold metallo-hydrolase -
FPL05_RS22155 4801327..4802616 - 1290 WP_016850773.1 tryptophan--tRNA ligase -
FPL05_RS22160 4802784..4802993 - 210 WP_003486601.1 CsbD family protein -
FPL05_RS22165 4803220..4803354 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
FPL05_RS22170 4803429..4803581 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
FPL05_RS22175 4803688..4804611 - 924 WP_003486608.1 arginase -
FPL05_RS22180 4804932..4805384 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
FPL05_RS22185 4805448..4805807 + 360 WP_003486613.1 hypothetical protein -
FPL05_RS22190 4805904..4806821 + 918 WP_016850774.1 hypothetical protein -
FPL05_RS22195 4806818..4807360 + 543 WP_003486615.1 GTPase -
FPL05_RS22205 4807798..4808481 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T134761 WP_005914328.1 NZ_CP041967:c4803354-4803220 [Xanthomonas citri pv. glycines]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T134761 NZ_CP041967:c4803354-4803220 [Xanthomonas citri pv. glycines]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGTTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT134761 WP_003486606.1 NZ_CP041967:c4803581-4803429 [Xanthomonas citri pv. glycines]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT134761 NZ_CP041967:c4803581-4803429 [Xanthomonas citri pv. glycines]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References