Detailed information of TA system TA134760

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 99224..99768
• Replicon: chromosome
• Accession: NZ_CP041967
• Organism: Xanthomonas citri pv. glycines strain K2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FPL05_RS00605
• Protein ID: WP_005928957.1
• Coordinates: 99469..99768 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A1D9ED60
• Locus tag: FPL05_RS00600
• Protein ID: WP_016849693.1
• Coordinates: 99224..99481 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FPL05_RS00585	94325..95824	-	1500	WP_029827796.1	ribonuclease H-like domain-containing protein	-
FPL05_RS00590	95821..98316	-	2496	WP_016849694.1	DEAD/DEAH box helicase	-
FPL05_RS00595	98494..99156	+	663	WP_005912558.1	hemolysin III family protein	-
FPL05_RS00600	99224..99481	+	258	WP_016849693.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FPL05_RS00605	99469..99768	+	300	WP_005928957.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FPL05_RS00615	99956..100854	-	899	Protein_84	SDR family NAD(P)-dependent oxidoreductase	-
FPL05_RS00620	100913..101650	-	738	WP_016849691.1	SDR family oxidoreductase	-
FPL05_RS00625	101776..102687	+	912	WP_016849690.1	LysR family transcriptional regulator	-
FPL05_RS00630	102884..103957	-	1074	WP_026006953.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11260.02 Da
• Isoelectric Point: 9.7235

>T134760 WP_005928957.1 NZ_CP041967:99469-99768 [Xanthomonas citri pv. glycines]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHIMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T134760 NZ_CP041967:99469-99768 [Xanthomonas citri pv. glycines]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGACCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACATCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9674.20 Da
• Isoelectric Point: 9.8271

>AT134760 WP_016849693.1 NZ_CP041967:99224-99481 [Xanthomonas citri pv. glycines]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQARQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT134760 NZ_CP041967:99224-99481 [Xanthomonas citri pv. glycines]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACGGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Antitoxin

• AlphaFold DB: A0A1D9ED60