Detailed information of TA system TA134755

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 99276..99820
• Replicon: chromosome
• Accession: NZ_CP041963
• Organism: Xanthomonas citri pv. glycines strain 1157

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FPL03_RS00445
• Protein ID: WP_005928957.1
• Coordinates: 99521..99820 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A1D9ED60
• Locus tag: FPL03_RS00440
• Protein ID: WP_016849693.1
• Coordinates: 99276..99533 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FPL03_RS00425	94395..95876	-	1482	WP_145592910.1	ribonuclease H-like domain-containing protein	-
FPL03_RS00430	95873..98368	-	2496	WP_016849694.1	DEAD/DEAH box helicase	-
FPL03_RS00435	98546..99208	+	663	WP_005912558.1	hemolysin III family protein	-
FPL03_RS00440	99276..99533	+	258	WP_016849693.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FPL03_RS00445	99521..99820	+	300	WP_005928957.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FPL03_RS00455	100008..100906	-	899	Protein_84	SDR family NAD(P)-dependent oxidoreductase	-
FPL03_RS00460	100965..101702	-	738	WP_016849691.1	SDR family oxidoreductase	-
FPL03_RS00465	101828..102739	+	912	WP_016849690.1	LysR family transcriptional regulator	-
FPL03_RS00470	102936..104009	-	1074	WP_026006953.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11260.02 Da
• Isoelectric Point: 9.7235

>T134755 WP_005928957.1 NZ_CP041963:99521-99820 [Xanthomonas citri pv. glycines]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHIMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T134755 NZ_CP041963:99521-99820 [Xanthomonas citri pv. glycines]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGACCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACATCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9674.20 Da
• Isoelectric Point: 9.8271

>AT134755 WP_016849693.1 NZ_CP041963:99276-99533 [Xanthomonas citri pv. glycines]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQARQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT134755 NZ_CP041963:99276-99533 [Xanthomonas citri pv. glycines]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACGGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Antitoxin

• AlphaFold DB: A0A1D9ED60