134752

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4648678..4649038 Replicon chromosome
Accession NZ_CP041961
Organism Xanthomonas citri pv. glycines strain 1018

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag FPL00_RS21085 Protein ID WP_005914328.1
Coordinates 4648678..4648812 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag FPL00_RS21090 Protein ID WP_003486606.1
Coordinates 4648886..4649038 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPL00_RS21065 4643829..4645520 - 1692 WP_016850771.1 M20/M25/M40 family metallo-hydrolase -
FPL00_RS21070 4645712..4646746 - 1035 WP_016850772.1 MBL fold metallo-hydrolase -
FPL00_RS21075 4646785..4648074 - 1290 WP_016850773.1 tryptophan--tRNA ligase -
FPL00_RS21080 4648242..4648451 - 210 WP_003486601.1 CsbD family protein -
FPL00_RS21085 4648678..4648812 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
FPL00_RS21090 4648886..4649038 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
FPL00_RS21095 4649145..4650068 - 924 WP_003486608.1 arginase -
FPL00_RS21100 4650389..4650841 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
FPL00_RS21105 4650905..4651264 + 360 WP_003486613.1 hypothetical protein -
FPL00_RS21110 4651361..4652278 + 918 WP_016850774.1 hypothetical protein -
FPL00_RS21115 4652275..4652817 + 543 WP_003486615.1 GTPase -
FPL00_RS21125 4653255..4653938 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T134752 WP_005914328.1 NZ_CP041961:c4648812-4648678 [Xanthomonas citri pv. glycines]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T134752 NZ_CP041961:c4648812-4648678 [Xanthomonas citri pv. glycines]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGTTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT134752 WP_003486606.1 NZ_CP041961:c4649038-4648886 [Xanthomonas citri pv. glycines]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT134752 NZ_CP041961:c4649038-4648886 [Xanthomonas citri pv. glycines]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References