Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2022372..2022643 Replicon chromosome
Accession NZ_CP041955
Organism Escherichia coli strain EC2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2022502..2022605 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2022372..2022643 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOZ67_RS09600 2018927..2019589 - 663 WP_000944256.1 exodeoxyribonuclease X -
FOZ67_RS09605 2019613..2020269 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FOZ67_RS09610 2020371..2020601 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FOZ67_RS09615 2020740..2021114 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FOZ67_RS09620 2021118..2021990 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
FOZ67_RS09625 2022003..2022344 + 342 WP_000976476.1 YebY family protein -
- 2022372..2022643 - 272 - - Antitoxin
- 2022502..2022605 + 104 - - Toxin
FOZ67_RS09630 2022740..2023396 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FOZ67_RS09635 2023397..2023588 - 192 WP_000457842.1 YebW family protein -
FOZ67_RS09640 2023693..2023929 - 237 WP_001295499.1 DUF1480 family protein -
FOZ67_RS09645 2024047..2025486 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T134729 NZ_CP041955:2022502-2022605 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT134729 NZ_CP041955:c2022643-2022372 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References