Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-DUF971
Location 1562491..1563070 Replicon chromosome
Accession NZ_CP041933
Organism Pseudomonas sp. BJP69

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FPB55_RS07280 Protein ID WP_144189605.1
Coordinates 1562765..1563070 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FPB55_RS07275 Protein ID WP_009683681.1
Coordinates 1562491..1562784 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPB55_RS07250 1557513..1558388 + 876 WP_064314548.1 carboxylate/amino acid/amine transporter -
FPB55_RS07255 1558390..1558803 + 414 WP_009683095.1 aminoacyl-tRNA hydrolase -
FPB55_RS07260 1558883..1560184 - 1302 WP_009683094.1 mechanosensitive ion channel family protein -
FPB55_RS07265 1560288..1561649 + 1362 WP_144187887.1 DEAD/DEAH box helicase -
FPB55_RS07270 1562025..1562300 - 276 WP_054914022.1 hypothetical protein -
FPB55_RS07275 1562491..1562784 - 294 WP_009683681.1 putative addiction module antidote protein Antitoxin
FPB55_RS07280 1562765..1563070 - 306 WP_144189605.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FPB55_RS07285 1563259..1563654 + 396 WP_009683679.1 hypothetical protein -
FPB55_RS07290 1563761..1564687 + 927 WP_144187889.1 DMT family transporter -
FPB55_RS07295 1565132..1566511 - 1380 WP_054914019.1 sodium:solute symporter -
FPB55_RS07300 1566617..1567567 - 951 WP_054881882.1 agmatinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-90)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11383.95 Da        Isoelectric Point: 10.5329

>T134690 WP_144189605.1 NZ_CP041933:c1563070-1562765 [Pseudomonas sp. BJP69]
IESSSFRHWVSGLRDVSARTRIIARINRLMEGLPGDVSPVGHGVSELRVHYGPGYRVYFHQAGSTFVILLCGGDKSSQQR
DIKAAHHILRSWRMQNDTNLL

Download         Length: 306 bp

>T134690 NZ_CP041933:c1563070-1562765 [Pseudomonas sp. BJP69]
ATCGAATCCAGCAGTTTCAGACATTGGGTGAGCGGGCTCCGGGATGTTAGCGCCAGAACGCGAATCATTGCTCGGATCAA
CCGATTGATGGAGGGCCTGCCTGGCGATGTATCACCGGTTGGCCACGGCGTCAGTGAACTCAGGGTCCACTATGGGCCCG
GCTACCGCGTATATTTCCACCAGGCGGGCAGTACGTTCGTCATTCTTTTGTGCGGCGGCGATAAAAGCAGCCAACAACGG
GACATCAAAGCAGCCCACCATATTCTGCGTTCGTGGAGGATGCAAAATGACACAAACCTTCTCTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10482.96 Da        Isoelectric Point: 6.2152

>AT134690 WP_009683681.1 NZ_CP041933:c1562784-1562491 [Pseudomonas sp. BJP69]
MTQTFSEFDPAEYLTTPEAIAVFMTDALETGDASYVAKAVGVVARAKGMSELAKDTGLSREQLYRSFSEHGNPTLKSFLT
VMKALGIHMTARPHIAG

Download         Length: 294 bp

>AT134690 NZ_CP041933:c1562784-1562491 [Pseudomonas sp. BJP69]
ATGACACAAACCTTCTCTGAATTCGATCCCGCCGAATACCTCACCACTCCTGAAGCAATCGCCGTGTTCATGACTGACGC
CCTGGAGACCGGGGATGCCAGCTATGTCGCCAAAGCTGTCGGCGTAGTAGCGCGTGCCAAAGGCATGAGCGAGCTGGCAA
AAGACACAGGGCTATCTCGTGAACAGCTTTACCGGTCGTTCAGCGAGCATGGCAACCCAACCCTCAAATCGTTCCTGACC
GTGATGAAAGCATTGGGTATACACATGACAGCGCGTCCTCACATCGCAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References