129248

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5292596..5293263 Replicon chromosome
Accession NZ_CP041781
Organism Xanthomonas citri pv. glycines strain 8ra

Toxin (Protein)


Gene name vapC Uniprot ID M4U0C6
Locus tag FPK90_RS23995 Protein ID WP_005916679.1
Coordinates 5292847..5293263 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID M4U000
Locus tag FPK90_RS23990 Protein ID WP_005916676.1
Coordinates 5292596..5292850 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPK90_RS23965 5288702..5288911 + 210 WP_108350128.1 RNA 2'-phosphotransferase -
FPK90_RS23970 5289094..5290359 + 1266 WP_016849472.1 cardiolipin synthase B -
FPK90_RS23975 5290385..5290912 - 528 WP_005916668.1 hypothetical protein -
FPK90_RS23980 5291151..5291357 + 207 WP_003489327.1 hypothetical protein -
FPK90_RS23985 5291344..5292450 + 1107 WP_005916674.1 type II toxin-antitoxin system RelE/ParE family toxin -
FPK90_RS23990 5292596..5292850 + 255 WP_005916676.1 Arc family DNA-binding protein Antitoxin
FPK90_RS23995 5292847..5293263 + 417 WP_005916679.1 type II toxin-antitoxin system VapC family toxin Toxin
FPK90_RS24000 5293385..5293657 - 273 WP_124632111.1 hypothetical protein -
FPK90_RS24005 5293670..5293930 - 261 WP_124632112.1 hypothetical protein -
FPK90_RS24010 5294187..5295806 + 1620 WP_016849230.1 enterochelin esterase -
FPK90_RS24015 5295910..5296308 - 399 WP_004429277.1 DUF2384 domain-containing protein -
FPK90_RS24020 5296624..5297055 + 432 WP_016849229.1 hypothetical protein -
FPK90_RS24025 5297084..5297410 - 327 Protein_4441 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14795.09 Da        Isoelectric Point: 5.6920

>T129248 WP_005916679.1 NZ_CP041781:5292847-5293263 [Xanthomonas citri pv. glycines]
VILLDTNVISELWRPQPNPQVVAWIDAQAVETLFLSVVTVAELRFGIAVMPKGRKRSTLHARLEGEVLPLFDGRLLAFDL
DASHAFAALASKARTAGLTLGRADAYIAATAAAQGLTVATRDTAPFEAMALDVINPWS

Download         Length: 417 bp

>T129248 NZ_CP041781:5292847-5293263 [Xanthomonas citri pv. glycines]
GTGATCCTGCTCGATACCAATGTCATCTCCGAACTTTGGCGGCCTCAGCCTAATCCGCAAGTCGTCGCCTGGATCGATGC
ACAAGCTGTCGAGACACTGTTCCTGTCGGTCGTGACGGTGGCTGAACTCCGTTTCGGTATTGCCGTGATGCCCAAGGGCC
GAAAGCGATCCACCTTGCATGCTCGGTTGGAGGGCGAGGTATTGCCACTGTTCGACGGGCGCCTGCTCGCATTCGATCTG
GATGCATCACACGCATTTGCGGCGCTTGCATCGAAAGCCAGAACCGCAGGACTCACACTCGGGCGCGCCGATGCCTACAT
CGCTGCAACGGCAGCCGCGCAAGGATTGACCGTTGCCACTCGCGACACGGCACCATTCGAGGCGATGGCGTTAGACGTCA
TTAACCCTTGGAGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8996.53 Da        Isoelectric Point: 11.3362

>AT129248 WP_005916676.1 NZ_CP041781:5292596-5292850 [Xanthomonas citri pv. glycines]
MPSFTVRNIPDDVHRAIRARAALHGRSTEAEIRAILELAAKPADRVKLGSLLVSIGRDAGLTAKEANAFDKLRGKAAIKP
IGLK

Download         Length: 255 bp

>AT129248 NZ_CP041781:5292596-5292850 [Xanthomonas citri pv. glycines]
ATGCCTTCTTTCACCGTCCGCAATATCCCAGACGACGTGCATCGCGCGATCCGCGCGCGGGCTGCACTTCATGGCCGCAG
CACCGAAGCGGAGATCCGCGCAATCCTTGAATTGGCGGCCAAACCCGCAGACCGGGTCAAACTCGGCTCACTGCTGGTGA
GCATCGGCCGCGACGCCGGCCTGACCGCAAAAGAGGCCAATGCCTTCGACAAGCTGCGCGGCAAGGCGGCGATCAAGCCG
ATCGGTCTGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB M4U0C6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YKJ0

References