129247

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4879241..4879602 Replicon chromosome
Accession NZ_CP041781
Organism Xanthomonas citri pv. glycines strain 8ra

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag FPK90_RS22270 Protein ID WP_005914328.1
Coordinates 4879241..4879375 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag FPK90_RS22275 Protein ID WP_003486606.1
Coordinates 4879450..4879602 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPK90_RS22250 4874392..4876083 - 1692 WP_016850771.1 M20/M25/M40 family metallo-hydrolase -
FPK90_RS22255 4876275..4877309 - 1035 WP_016850772.1 MBL fold metallo-hydrolase -
FPK90_RS22260 4877348..4878637 - 1290 WP_016850773.1 tryptophan--tRNA ligase -
FPK90_RS22265 4878805..4879014 - 210 WP_003486601.1 CsbD family protein -
FPK90_RS22270 4879241..4879375 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
FPK90_RS22275 4879450..4879602 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
FPK90_RS22280 4879709..4880632 - 924 WP_003486608.1 arginase -
FPK90_RS22285 4880953..4881405 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
FPK90_RS22290 4881469..4881828 + 360 WP_003486613.1 hypothetical protein -
FPK90_RS22295 4881925..4882842 + 918 WP_016850774.1 hypothetical protein -
FPK90_RS22300 4882839..4883381 + 543 WP_003486615.1 GTPase -
FPK90_RS22310 4883819..4884502 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T129247 WP_005914328.1 NZ_CP041781:c4879375-4879241 [Xanthomonas citri pv. glycines]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T129247 NZ_CP041781:c4879375-4879241 [Xanthomonas citri pv. glycines]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGTTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT129247 WP_003486606.1 NZ_CP041781:c4879602-4879450 [Xanthomonas citri pv. glycines]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT129247 NZ_CP041781:c4879602-4879450 [Xanthomonas citri pv. glycines]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References