Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 51030..51564 Replicon plasmid unnamed1
Accession NZ_CP041780
Organism Burkholderia sp. MS455

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FPJ27_RS35555 Protein ID WP_204426452.1
Coordinates 51265..51564 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FPJ27_RS35550 Protein ID WP_204426451.1
Coordinates 51030..51275 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPJ27_RS35530 47222..48430 + 1209 WP_204426447.1 AAA family ATPase -
FPJ27_RS35535 48427..49395 + 969 WP_204426448.1 ParB/RepB/Spo0J family partition protein -
FPJ27_RS35540 50046..50507 - 462 WP_204426449.1 hypothetical protein -
FPJ27_RS35545 50523..50774 - 252 WP_204426450.1 hypothetical protein -
FPJ27_RS35550 51030..51275 + 246 WP_204426451.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
FPJ27_RS35555 51265..51564 + 300 WP_204426452.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FPJ27_RS35560 51936..52250 + 315 WP_204426453.1 hypothetical protein -
FPJ27_RS35565 52347..52589 + 243 WP_204426454.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
FPJ27_RS35570 52586..52996 + 411 WP_204426455.1 type II toxin-antitoxin system VapC family toxin -
FPJ27_RS35575 53070..53270 + 201 WP_204426456.1 hypothetical protein -
FPJ27_RS35580 53486..53785 + 300 Protein_25 hypothetical protein -
FPJ27_RS35585 55477..56514 + 1038 WP_060715300.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..197398 197398


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-94)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11436.87 Da        Isoelectric Point: 5.5902

>T129243 WP_204426452.1 NZ_CP041780:51265-51564 [Burkholderia sp. MS455]
MSVKARTVRLTPLAEDDLEDIWAYTFERWSLELAEHYVGELAAAFDRLAAGEWVGRSSRAGDGCRRYPVGSHVVFYRETT
ETLDVIRVLHQRMDVDRHL

Download         Length: 300 bp

>T129243 NZ_CP041780:51265-51564 [Burkholderia sp. MS455]
ATGTCGGTTAAGGCTCGCACGGTACGCCTGACACCGCTGGCTGAGGACGATCTCGAGGATATCTGGGCCTACACGTTCGA
GCGCTGGTCGCTCGAGCTGGCCGAGCACTATGTCGGCGAGTTGGCCGCGGCGTTCGATCGGCTGGCGGCCGGCGAGTGGG
TGGGCCGGTCAAGCCGCGCGGGCGACGGCTGTCGGCGCTATCCGGTGGGCTCTCACGTGGTGTTCTATCGCGAAACGACC
GAGACCCTTGATGTGATCCGCGTGCTGCACCAGCGGATGGACGTCGACCGGCATTTGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8589.62 Da        Isoelectric Point: 7.2025

>AT129243 WP_204426451.1 NZ_CP041780:51030-51275 [Burkholderia sp. MS455]
MARNTSISLGDHLTQFVDTQVASGRYGSASDVVRAGLRLLETQEAELRALQEALKAGDASGAPATFDSQAFLARMRAKHV
G

Download         Length: 246 bp

>AT129243 NZ_CP041780:51030-51275 [Burkholderia sp. MS455]
ATGGCACGGAACACTTCAATCTCGCTGGGGGATCACCTGACCCAGTTCGTGGACACGCAGGTCGCGTCTGGCCGCTACGG
CTCTGCGAGCGATGTGGTGCGGGCCGGCCTGCGCCTACTCGAGACGCAGGAAGCCGAGTTGCGGGCGCTGCAGGAAGCGT
TGAAGGCCGGTGACGCTTCGGGCGCGCCGGCCACGTTCGACAGCCAGGCGTTCCTGGCCCGGATGCGGGCCAAGCATGTC
GGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References