Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-StbC |
Location | 2006123..2006778 | Replicon | chromosome |
Accession | NZ_CP041778 | ||
Organism | Burkholderia sp. MS455 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | FPJ27_RS13640 | Protein ID | WP_204421467.1 |
Coordinates | 2006123..2006542 (-) | Length | 140 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | FPJ27_RS13645 | Protein ID | WP_204423192.1 |
Coordinates | 2006539..2006778 (-) | Length | 80 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FPJ27_RS13615 | 2001499..2002293 | + | 795 | WP_204421464.1 | AraC family transcriptional regulator | - |
FPJ27_RS13620 | 2002503..2003471 | + | 969 | WP_204421465.1 | DMT family transporter | - |
FPJ27_RS13625 | 2003657..2004229 | + | 573 | WP_072442377.1 | permease | - |
FPJ27_RS13630 | 2004329..2004463 | - | 135 | WP_021158165.1 | entericidin A/B family lipoprotein | - |
FPJ27_RS13635 | 2004697..2005992 | + | 1296 | WP_204421466.1 | aspartate carbamoyltransferase | - |
FPJ27_RS13640 | 2006123..2006542 | - | 420 | WP_204421467.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
FPJ27_RS13645 | 2006539..2006778 | - | 240 | WP_204423192.1 | Arc family DNA-binding protein | Antitoxin |
FPJ27_RS13650 | 2007090..2009327 | + | 2238 | WP_204421468.1 | TonB-dependent siderophore receptor | - |
FPJ27_RS13655 | 2009331..2010086 | + | 756 | WP_204421469.1 | sel1 repeat family protein | - |
FPJ27_RS13660 | 2010083..2010766 | + | 684 | WP_204421470.1 | Fe2+-dependent dioxygenase | - |
FPJ27_RS13665 | 2010846..2011268 | - | 423 | WP_034180480.1 | amino acid-binding protein | - |
FPJ27_RS13670 | 2011475..2011714 | + | 240 | WP_034180481.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 15249.65 Da Isoelectric Point: 5.9026
>T129237 WP_204421467.1 NZ_CP041778:c2006542-2006123 [Burkholderia sp. MS455]
MILVDTNVISEPLRREPSAAVIEWLDAQNVETLFLAAISLAEMRFGVAVLPEGRRREWLHQSIEQRVVPLFRGRILPFDD
AASKAYASLRARARVAGSAIAPVDCFIAATAEANGLIVATRDVAPFEAVGLRVIDPWAR
MILVDTNVISEPLRREPSAAVIEWLDAQNVETLFLAAISLAEMRFGVAVLPEGRRREWLHQSIEQRVVPLFRGRILPFDD
AASKAYASLRARARVAGSAIAPVDCFIAATAEANGLIVATRDVAPFEAVGLRVIDPWAR
Download Length: 420 bp
>T129237 NZ_CP041778:c2006542-2006123 [Burkholderia sp. MS455]
ATGATCCTTGTTGATACGAATGTCATTTCCGAACCCCTGCGACGCGAGCCGAGCGCAGCGGTGATCGAGTGGCTCGATGC
CCAGAACGTCGAGACGCTGTTTCTGGCTGCAATCAGTCTCGCGGAGATGCGATTCGGCGTGGCTGTATTGCCGGAAGGGC
GCAGGCGCGAGTGGCTGCATCAAAGCATCGAGCAGCGTGTCGTGCCGCTGTTTCGAGGCCGAATCCTGCCGTTCGACGAT
GCGGCGAGCAAAGCGTATGCGAGCCTGCGGGCTCGGGCCCGCGTCGCAGGTAGCGCGATCGCGCCTGTCGATTGTTTTAT
CGCCGCCACGGCCGAGGCGAACGGCCTGATCGTGGCCACGCGCGATGTCGCGCCGTTCGAGGCGGTGGGGCTTCGCGTGA
TCGATCCGTGGGCGCGGTAG
ATGATCCTTGTTGATACGAATGTCATTTCCGAACCCCTGCGACGCGAGCCGAGCGCAGCGGTGATCGAGTGGCTCGATGC
CCAGAACGTCGAGACGCTGTTTCTGGCTGCAATCAGTCTCGCGGAGATGCGATTCGGCGTGGCTGTATTGCCGGAAGGGC
GCAGGCGCGAGTGGCTGCATCAAAGCATCGAGCAGCGTGTCGTGCCGCTGTTTCGAGGCCGAATCCTGCCGTTCGACGAT
GCGGCGAGCAAAGCGTATGCGAGCCTGCGGGCTCGGGCCCGCGTCGCAGGTAGCGCGATCGCGCCTGTCGATTGTTTTAT
CGCCGCCACGGCCGAGGCGAACGGCCTGATCGTGGCCACGCGCGATGTCGCGCCGTTCGAGGCGGTGGGGCTTCGCGTGA
TCGATCCGTGGGCGCGGTAG
Antitoxin
Download Length: 80 a.a. Molecular weight: 8645.82 Da Isoelectric Point: 5.6864
>AT129237 WP_204423192.1 NZ_CP041778:c2006778-2006539 [Burkholderia sp. MS455]
MPVITVRNLPDEVHRALRVRAAQHGRSTEAEVRDILEQAVLPGGRLKLGTLLAEIGREAGGVDVDVQRDKTSTDPMSFE
MPVITVRNLPDEVHRALRVRAAQHGRSTEAEVRDILEQAVLPGGRLKLGTLLAEIGREAGGVDVDVQRDKTSTDPMSFE
Download Length: 240 bp
>AT129237 NZ_CP041778:c2006778-2006539 [Burkholderia sp. MS455]
ATGCCGGTGATCACCGTTCGAAATTTGCCTGATGAAGTGCATCGCGCACTTCGGGTTCGCGCGGCCCAGCACGGACGAAG
CACCGAAGCCGAGGTACGTGACATTCTCGAACAGGCCGTCCTGCCAGGCGGGCGGCTCAAGCTGGGAACGTTGCTGGCGG
AAATCGGGCGGGAGGCTGGTGGAGTCGATGTCGACGTCCAGCGCGACAAGACGTCAACCGATCCGATGAGCTTCGAATGA
ATGCCGGTGATCACCGTTCGAAATTTGCCTGATGAAGTGCATCGCGCACTTCGGGTTCGCGCGGCCCAGCACGGACGAAG
CACCGAAGCCGAGGTACGTGACATTCTCGAACAGGCCGTCCTGCCAGGCGGGCGGCTCAAGCTGGGAACGTTGCTGGCGG
AAATCGGGCGGGAGGCTGGTGGAGTCGATGTCGACGTCCAGCGCGACAAGACGTCAACCGATCCGATGAGCTTCGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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