Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 671512..672153 Replicon chromosome
Accession NZ_CP041778
Organism Burkholderia sp. MS455

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FPJ27_RS07530 Protein ID WP_047901477.1
Coordinates 671815..672153 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FPJ27_RS07525 Protein ID WP_204422510.1
Coordinates 671512..671811 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPJ27_RS07495 666556..666699 + 144 WP_175958602.1 hypothetical protein -
FPJ27_RS07500 666769..668040 + 1272 WP_204422508.1 Rieske 2Fe-2S domain-containing protein -
FPJ27_RS07505 668055..668531 + 477 WP_014900133.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
FPJ27_RS07510 668549..668875 + 327 WP_034185113.1 non-heme iron oxygenase ferredoxin subunit -
FPJ27_RS07515 668865..670085 + 1221 WP_204422509.1 FAD-dependent oxidoreductase -
FPJ27_RS07520 670177..671463 + 1287 WP_072439283.1 DUF445 domain-containing protein -
FPJ27_RS07525 671512..671811 - 300 WP_204422510.1 putative addiction module antidote protein Antitoxin
FPJ27_RS07530 671815..672153 - 339 WP_047901477.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FPJ27_RS07535 672482..674122 + 1641 WP_204422511.1 acetolactate synthase large subunit -
FPJ27_RS07540 674152..675585 + 1434 WP_175958610.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(26-98)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12625.51 Da        Isoelectric Point: 8.9480

>T129232 WP_047901477.1 NZ_CP041778:c672153-671815 [Burkholderia sp. MS455]
MVDILQSMPYSAPTFSIRTTDVFDAWFAGLQDRVAKRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRG
TIWVILLCGGDKSTQQADIRAAHAMLAHLDME

Download         Length: 339 bp

>T129232 NZ_CP041778:c672153-671815 [Burkholderia sp. MS455]
ATGGTTGACATACTGCAATCAATGCCCTACAGTGCGCCTACGTTCAGCATCCGGACCACCGACGTCTTCGACGCATGGTT
TGCCGGCCTGCAGGATCGCGTCGCGAAGCGCCGCATCCAGGCACGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACT
GGAAATCCGCCGGCTCGCCGGTCGTCGAAATGCGTATCGACCATGGCCCCGGCTATCGCGTCTACTACGTCCGGCGCGGA
ACGATCTGGGTCATCCTGCTCTGCGGCGGCGATAAATCGACGCAACAGGCCGACATACGCGCCGCGCACGCGATGCTCGC
GCATCTCGACATGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10647.98 Da        Isoelectric Point: 6.3205

>AT129232 WP_204422510.1 NZ_CP041778:c671811-671512 [Burkholderia sp. MS455]
MNKISTRPWDSADHLQTEDDMADYFEACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGSKAHA

Download         Length: 300 bp

>AT129232 NZ_CP041778:c671811-671512 [Burkholderia sp. MS455]
ATGAACAAGATCAGCACCCGCCCGTGGGATTCGGCCGACCATCTGCAAACCGAAGACGACATGGCCGACTACTTCGAAGC
CTGCCTGCAAGAGGCCGGCGACGATCCGGCCTTCATCGCGCACGCGCTCGGCGTGATCGCACGCGCACGCGGCATGTCGC
AGGTCGCGCGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCACTCGGCCTGCAACTGCACGGCTCGAAAGCGCACGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References