Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3218139..3218805 Replicon chromosome
Accession NZ_CP041764
Organism Serratia rhizosphaerae strain KUDC3025

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FO014_RS15000 Protein ID WP_160030105.1
Coordinates 3218386..3218805 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FO014_RS14995 Protein ID WP_105232395.1
Coordinates 3218139..3218405 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FO014_RS14970 3213295..3213948 + 654 WP_160030101.1 hypothetical protein -
FO014_RS14975 3213945..3215264 + 1320 WP_160030102.1 MHS family MFS transporter -
FO014_RS14980 3215296..3215904 - 609 WP_160030103.1 HD domain-containing protein -
FO014_RS14985 3216099..3216779 + 681 WP_160030104.1 hemolysin III family protein -
FO014_RS14990 3216816..3217808 - 993 WP_105232396.1 tRNA-modifying protein YgfZ -
FO014_RS14995 3218139..3218405 + 267 WP_105232395.1 FAD assembly factor SdhE Antitoxin
FO014_RS15000 3218386..3218805 + 420 WP_160030105.1 hypothetical protein Toxin
FO014_RS15005 3218836..3219354 - 519 WP_105232393.1 flavodoxin FldB -
FO014_RS15010 3219446..3220345 + 900 WP_160030106.1 site-specific tyrosine recombinase XerD -
FO014_RS15015 3220373..3221089 + 717 WP_015673664.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FO014_RS15020 3221102..3222832 + 1731 WP_160030107.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16454.43 Da        Isoelectric Point: 11.2273

>T129191 WP_160030105.1 NZ_CP041764:3218386-3218805 [Serratia rhizosphaerae]
VAQWRCDVRISWRTQLISLLAHGALILLILISPWPESYDPVWLLLLTLVVFECIRSQTRIASRQGELRLLSAPQRVIWQG
KEWRLVRRPWMLRYGMLLTLQASGKRKRRRLWLASDCISSAEWRQLCQRMRLAEDESEG

Download         Length: 420 bp

>T129191 NZ_CP041764:3218386-3218805 [Serratia rhizosphaerae]
GTGGCCCAGTGGCGATGTGATGTCCGCATCTCCTGGCGTACTCAGCTTATCTCGTTGTTGGCGCATGGCGCGCTGATATT
GCTGATCCTGATTTCGCCGTGGCCGGAGAGTTACGATCCGGTCTGGCTATTGCTGCTGACGCTGGTGGTTTTTGAATGTA
TTCGCAGTCAGACGCGTATCGCATCGCGCCAGGGGGAGCTGCGTCTGCTCTCTGCGCCGCAGCGGGTAATCTGGCAAGGC
AAGGAGTGGCGGCTGGTCCGGCGCCCATGGATGCTGCGCTACGGCATGCTGCTGACGCTGCAGGCGAGCGGGAAGCGTAA
ACGCCGGCGGCTGTGGCTGGCGTCGGACTGCATCAGCAGCGCGGAGTGGCGGCAGTTGTGCCAGCGGATGCGGCTGGCCG
AGGATGAATCTGAAGGCTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10405.90 Da        Isoelectric Point: 5.0964

>AT129191 WP_105232395.1 NZ_CP041764:3218139-3218405 [Serratia rhizosphaerae]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSEEDKALFVRLLQCDDPDLFNWLMNHGAPQDAELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT129191 NZ_CP041764:3218139-3218405 [Serratia rhizosphaerae]
ATGGATATTAATAACAAAGCGCGTATTCACTGGGCTTGCCGCCGTGGAATGCGTGAGCTGGACATCTCCATCATGCCGTT
TTTCGAGCATGAGTACGATTCATTGAGCGAAGAGGATAAGGCGCTGTTCGTGCGTTTGTTGCAGTGTGACGATCCCGATC
TGTTTAACTGGCTGATGAATCATGGCGCCCCGCAGGACGCTGAATTGCAAAGAATGGTGACGCTGATCCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References