Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 4703..5289 Replicon plasmid unnamed2
Accession NZ_CP041756
Organism Pseudomonas sp. KBS0707

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FFH21_RS29580 Protein ID WP_054073125.1
Coordinates 4703..5002 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FFH21_RS29585 Protein ID WP_054073126.1
Coordinates 4999..5289 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFH21_RS29560 1..1314 + 1314 WP_116831358.1 replication initiation protein -
FFH21_RS29565 1453..1878 + 426 WP_046720382.1 S24 family peptidase -
FFH21_RS29570 1871..3154 + 1284 WP_054073200.1 Y-family DNA polymerase -
FFH21_RS29575 3507..4541 - 1035 WP_011168770.1 IS110-like element ISPsy16 family transposase -
FFH21_RS29580 4703..5002 + 300 WP_054073125.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FFH21_RS29585 4999..5289 + 291 WP_054073126.1 putative addiction module antidote protein Antitoxin
FFH21_RS29590 5361..5699 + 339 WP_054073127.1 hypothetical protein -
FFH21_RS29595 6174..6830 + 657 WP_054073128.1 hypothetical protein -
FFH21_RS29600 6885..7139 + 255 WP_054073129.1 hypothetical protein -
FFH21_RS29610 7534..8073 + 540 WP_054073130.1 hypothetical protein -
FFH21_RS29615 8332..8973 + 642 WP_054073131.1 SOS response-associated peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..41171 41171
- flank IS/Tn - - 3507..4541 1034


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(11-93)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11167.91 Da        Isoelectric Point: 10.2244

>T129165 WP_054073125.1 NZ_CP041756:4703-5002 [Pseudomonas sp. KBS0707]
MIEIKQTATFMSWESKLKDQRAKAAIAARIFRLANGLPGDVSPVGQGVSELRIHYGPGYRVYFQQRGMEIVILLCGGDKS
SQSRDIEMAKRLANEWRPQ

Download         Length: 300 bp

>T129165 NZ_CP041756:4703-5002 [Pseudomonas sp. KBS0707]
ATGATTGAAATTAAACAAACCGCTACGTTCATGAGCTGGGAAAGCAAGCTGAAGGATCAGCGGGCAAAGGCCGCAATTGC
TGCACGCATTTTTCGCCTGGCTAATGGTCTACCTGGGGACGTGTCACCAGTCGGCCAAGGTGTGAGCGAGTTGAGAATTC
ACTACGGCCCAGGCTATCGAGTTTACTTTCAACAGCGCGGGATGGAGATCGTTATCCTGCTGTGTGGTGGAGACAAGAGC
AGCCAGTCCAGGGACATAGAAATGGCGAAACGCCTAGCAAATGAGTGGAGGCCGCAATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10301.77 Da        Isoelectric Point: 4.5238

>AT129165 WP_054073126.1 NZ_CP041756:4999-5289 [Pseudomonas sp. KBS0707]
MTDPIYDYDPAQALDGPEAIAVFIADALDTGDAAYIAKAMGVVARAKGMTELANETGLAREQLYKSFSERGNPTLKTMLV
VMRALGVDLTARPHTQ

Download         Length: 291 bp

>AT129165 NZ_CP041756:4999-5289 [Pseudomonas sp. KBS0707]
ATGACCGATCCAATTTATGACTACGATCCTGCGCAAGCGCTGGATGGCCCAGAGGCAATAGCCGTGTTCATCGCAGATGC
TCTGGACACTGGAGATGCTGCCTATATCGCCAAAGCTATGGGTGTGGTTGCTCGCGCTAAGGGCATGACAGAGCTTGCCA
ATGAGACGGGGTTGGCTAGAGAGCAGCTTTACAAGTCGTTCAGTGAACGCGGGAATCCTACGCTGAAGACCATGCTGGTG
GTGATGCGAGCGCTAGGAGTTGATTTGACCGCTCGACCGCATACGCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References