Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE-Phd
Location 82145..82756 Replicon plasmid unnamed1
Accession NZ_CP041755
Organism Pseudomonas sp. KBS0707

Toxin (Protein)


Gene name PfiT Uniprot ID Q48B85
Locus tag FFH21_RS29245 Protein ID WP_004666861.1
Coordinates 82406..82756 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID Q48B86
Locus tag FFH21_RS29240 Protein ID WP_004662018.1
Coordinates 82145..82393 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFH21_RS29220 78409..78711 + 303 WP_050772301.1 hypothetical protein -
FFH21_RS29225 78668..79993 + 1326 WP_011282502.1 SIR2 family protein -
FFH21_RS29230 80009..80833 + 825 WP_134933068.1 hypothetical protein -
FFH21_RS29235 80851..81813 - 963 WP_054072957.1 tyrosine-type recombinase/integrase -
FFH21_RS29240 82145..82393 + 249 WP_004662018.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FFH21_RS29245 82406..82756 + 351 WP_004666861.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FFH21_RS30140 83916..84080 + 165 WP_004666862.1 hypothetical protein -
FFH21_RS29255 84191..85225 + 1035 WP_011168770.1 IS110-like element ISPsy16 family transposase -
FFH21_RS29260 85797..87746 + 1950 WP_011282440.1 EAL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..131974 131974


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-101)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12950.95 Da        Isoelectric Point: 4.3843

>T129162 WP_004666861.1 NZ_CP041755:82406-82756 [Pseudomonas sp. KBS0707]
MNTFALRFTEVAQQSIEDQVEHLAITQGFSLAAQRINTLIDVIQDKLLSTPLGYPVSPQLSELGVLHYRELNADGYRIFY
EVMDADGVTVIVVVLVISGKQSVEQALIRYCLLQPI

Download         Length: 351 bp

>T129162 NZ_CP041755:82406-82756 [Pseudomonas sp. KBS0707]
ATGAACACGTTTGCACTACGCTTTACCGAGGTTGCCCAGCAAAGCATTGAAGATCAGGTCGAGCACCTGGCTATCACTCA
GGGATTCTCATTAGCTGCTCAACGTATAAATACCCTGATCGATGTCATCCAGGACAAGCTCTTGTCCACCCCGTTGGGCT
ACCCGGTCAGTCCTCAATTGAGTGAGCTGGGCGTACTGCATTATCGTGAGTTGAATGCTGACGGATACCGGATCTTTTAT
GAGGTGATGGATGCTGATGGCGTTACCGTCATCGTCGTGGTGCTTGTCATTAGTGGAAAACAAAGTGTTGAACAGGCACT
CATCCGTTACTGCCTGCTTCAACCTATTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9352.70 Da        Isoelectric Point: 9.8450

>AT129162 WP_004662018.1 NZ_CP041755:82145-82393 [Pseudomonas sp. KBS0707]
MRVETISYLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDESIALVKLLAISSREYSQGKHCSTDELKARLSRRFA
QK

Download         Length: 249 bp

>AT129162 NZ_CP041755:82145-82393 [Pseudomonas sp. KBS0707]
ATGCGAGTTGAAACAATAAGTTATCTGAAACGTAACGCAGCCGACCTGCCTCTCGATGAGCCACTGGTTGTCACGCAAAA
CGGTGTCCCGGCCTACGTGGTGGAGTCTTACGCAGATCGTAAGCGCCGCGATGAGTCGATCGCCTTGGTAAAGCTCCTGG
CGATCAGTTCCCGCGAGTACTCCCAAGGCAAGCACTGTTCCACTGACGAACTTAAAGCCCGGTTGAGCAGGAGGTTTGCC
CAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q48B85

Antitoxin

Source ID Structure
AlphaFold DB A0A0N8T3U9

References