Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 59297..59766 Replicon plasmid unnamed1
Accession NZ_CP041755
Organism Pseudomonas sp. KBS0707

Toxin (Protein)


Gene name relE Uniprot ID Q48BA0
Locus tag FFH21_RS29095 Protein ID WP_002556029.1
Coordinates 59485..59766 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q48BA1
Locus tag FFH21_RS29090 Protein ID WP_002556028.1
Coordinates 59297..59485 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFH21_RS29065 54901..55350 + 450 WP_011282491.1 invasin protein AfaD -
FFH21_RS29070 55425..55985 + 561 WP_054073162.1 hypothetical protein -
FFH21_RS29075 57094..58197 + 1104 WP_004663854.1 IS5-like element ISPsy19 family transposase -
FFH21_RS29085 58484..59119 + 636 WP_011282469.1 recombinase family protein -
FFH21_RS29090 59297..59485 + 189 WP_002556028.1 hypothetical protein Antitoxin
FFH21_RS29095 59485..59766 + 282 WP_002556029.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FFH21_RS29100 59918..61465 - 1548 WP_041924905.1 glycoside hydrolase family 28 protein -
FFH21_RS29105 61549..61773 - 225 WP_041924893.1 carbon storage regulator -
FFH21_RS29110 61877..62059 - 183 WP_004661237.1 hypothetical protein -
FFH21_RS29115 62489..62803 - 315 WP_081002620.1 hypothetical protein -
FFH21_RS29120 62902..63186 - 285 WP_011282457.1 type III effector HopW1-1, truncated -
FFH21_RS29125 63349..63624 - 276 Protein_70 recombinase family protein -
FFH21_RS29130 64074..64523 - 450 WP_005760341.1 type II toxin-antitoxin system PemK/MazF family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..131974 131974
- flank IS/Tn - - 57094..58197 1103


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10675.35 Da        Isoelectric Point: 8.4392

>T129161 WP_002556029.1 NZ_CP041755:59485-59766 [Pseudomonas sp. KBS0707]
MLPVVWLSPALDDLREIATYIAWENPSAARRLKSLLQEAIEPVAEHPYLYRSGRAPGTRELVAHPNYVLVYRVTLKRIEV
VNVIHARQEYPSP

Download         Length: 282 bp

>T129161 NZ_CP041755:59485-59766 [Pseudomonas sp. KBS0707]
ATGCTGCCGGTGGTCTGGCTCAGTCCCGCACTGGATGATCTGCGCGAAATCGCAACCTACATCGCATGGGAAAACCCGAG
CGCAGCGCGCCGGTTGAAAAGCCTCCTGCAGGAGGCTATCGAGCCGGTAGCCGAACACCCCTATTTATATCGTTCTGGGC
GAGCGCCAGGCACTCGCGAGCTGGTGGCTCACCCAAACTACGTCTTGGTCTATCGTGTCACCCTCAAGCGCATCGAGGTC
GTGAACGTAATCCACGCTAGGCAGGAATACCCCTCTCCCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7043.86 Da        Isoelectric Point: 4.2550

>AT129161 WP_002556028.1 NZ_CP041755:59297-59485 [Pseudomonas sp. KBS0707]
MANLSPIVSEFETDEQAASYDRWFRAKVAASLADPRPAIPHDEVMAEIEALIDQVETQREKR

Download         Length: 189 bp

>AT129161 NZ_CP041755:59297-59485 [Pseudomonas sp. KBS0707]
ATGGCCAACCTCTCACCCATCGTTTCAGAATTCGAAACCGATGAACAGGCCGCAAGCTACGACCGCTGGTTTCGCGCCAA
GGTCGCCGCCAGTCTGGCCGATCCGCGTCCGGCCATCCCTCATGATGAGGTCATGGCGGAAATAGAAGCGCTGATCGATC
AGGTTGAAACCCAACGTGAGAAACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M9HVA1

Antitoxin

Source ID Structure
AlphaFold DB A0A2G9KWB9

References